目的 研究茵山蓮顆粒聯(lián)合注射用生長抑素治療急性胰腺炎的臨床療效。方法 選取2015年6月—2017年6月開灤總醫(yī)院收治的急性胰腺炎患者120例為研究對象，隨機(jī)將所有研究對象分為對照組和治療組，每組各60例。對照組微量泵靜脈注射注射用生長抑素，首次100 μg，而后以50 μg/h勻速泵入。治療組在對照組治療基礎(chǔ)上口服茵山蓮顆粒，2袋/次，2次/d。兩組患者均連續(xù)治療14 d。觀察兩組的臨床療效，比較兩組的臨床癥狀消失時(shí)間和生化指標(biāo)。結(jié)果 治療后，對照組和治療組的總有效率分別為80.00%、95.00%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組嘔吐、腹脹、高熱、無便、上腹壓痛消失時(shí)間短于對照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組脂肪酶、血淀粉酶、白細(xì)胞數(shù)、腫瘤壞死因子-α（TNF-α）、白細(xì)胞介素-6（IL-6）水平顯著下降，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組生化指標(biāo)明顯低于對照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 茵山蓮顆粒聯(lián)合注射用生長抑素治療急性胰腺炎具有較好的臨床療效，能改善臨床癥狀，調(diào)節(jié)生化指標(biāo)，安全性較高，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To study the clinical effect of Yinshanlian Granules combined with Somatostatin for injection in treatment of acute pancreatitis. Methods Patients (120 cases) with acute pancreatitis in Kailuan General Hospital from June 2015 to June 2017 were randomly divided into control and treatment groups, and each group had 60 cases. Patients in the control group were micropump intravenous injection administered with Somatostatin for injection, first dosage 100 μg, and then 50 μg/h at uniform speed. Patients in the treatment group were po administered with Yinshanlian Granules on the basis of the control group, 2 bags/time, twice daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacies were evaluated, and clinical symptoms disappeared time and biochemical indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 80.00% and 95.00%, respectively, and there was difference between two groups (P < 0.05). After treatment, the clinical symptoms disappeared times of vomiting, abdominal distention, high fever, defecation, and upper abdominal pain in the treatment group were shorter than those in the control group, and there was difference between two groups (P < 0.05). After treatment, the levels of lipase, blood amylase, white blood cell number, TNF-α, and IL-6 in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Yinshanlian Granules combined with Somatostatin for injection has clinical curative effect in treatment of acute pancreatitis, can improve clinical symptoms, and regulate biochemical indexes, with good safety, which has a certain clinical application value.