[關(guān)鍵詞]
[摘要]
目的 探討宮炎康顆粒聯(lián)合甲硝唑氯化鈉注射液治療慢性盆腔炎的臨床療效。方法 選取2016年5月-2017年1月于天津市第一醫(yī)院進(jìn)行治療的盆腔炎患者92例為研究對象,采用隨機(jī)數(shù)表法將所有患者分為對照組和治療組,每組各46例。對照組靜脈滴注甲硝唑氯化鈉注射液,0.5 g/次,2次/d。治療組在對照組基礎(chǔ)上口服宮炎康顆粒,18 g/次,2次/d。兩組患者均持續(xù)治療2周。觀察兩組的臨床療效,比較兩組的臨床癥狀評分和血清指標(biāo)。結(jié)果 治療后,對照組和治療組的總有效率分別為80.4%、93.5%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組小腹疼痛、下腹墜脹、白帶量、腰骶脹痛評分和總分明顯降低,同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療組這些臨床癥狀評分明顯低于對照組,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組血清降鈣素原(PCT)、C-反應(yīng)蛋白(CRP)、紅細(xì)胞沉降率(ESR)水平顯著降低,同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療組這些血清指標(biāo)水平明顯低于對照組,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 宮炎康顆粒聯(lián)合甲硝唑氯化鈉注射液治療慢性盆腔炎具有較好的療效,能改善臨床癥狀,降低血清PCT、CRP、ESR水平,具有一定的臨床推廣應(yīng)用價(jià)值。
[Key word]
[Abstract]
Objective To investigate clinical curative effect of Gongyankang Granules combined with Metronidazole and Sodium Chloride Injection in treatment of chronic pelvic inflammatory disease. Methods Patients (92 cases) with chronic pelvic inflammatory disease in Tianjin First Hospital from May 2016 to January 2017 were randomly divided into control and treatment groups, and each group had 46 cases. Patients in the control group were iv administered with Metronidazole and Sodium Chloride Injection, 0.5 g/time, twice daily. Patients in the treatment group were po administered with Gongyankang Granules on the basis of the control group, 18 g/time, twice daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacies were evaluated, and clinical symptom scores and serum indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 80.4% and 93.5%, respectively, and there was difference between two groups (P<0.05). After treatment, the scores of lower abdominal pain, lower abdominal distention, leucorrhea amount, and lumbosacral distending pain, and total score in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the clinical symptom scores in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the levels of PCT, CRP, and ESR in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the serum indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Gongyankang Granules combined with Metronidazole and Sodium Chloride Injection has clinical curative effect in treatment of chronic pelvic inflammatory disease, can improve clinical symptoms, decrease the levels of PCT, CRP, and ESR, which has a certain clinical application value.
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