目的 探討康復(fù)新液聯(lián)合琥珀酸索利那新片治療前列腺電切術(shù)后膀胱痙攣的臨床療效。方法 選取2017年1月-2018年1月河北省滄州中西醫(yī)結(jié)合醫(yī)院收治的前列腺電切術(shù)術(shù)后膀胱痙攣患者100例為研究對(duì)象，根據(jù)隨機(jī)區(qū)組設(shè)計(jì)法將患者分為對(duì)照組和治療組，每組各50例。對(duì)照組于術(shù)后當(dāng)天口服琥珀酸索利那新片，5 mg/次，1次/d，尿管拔除后用生理鹽水持續(xù)沖洗膀胱。治療組在對(duì)照組治療的基礎(chǔ)上口服康復(fù)新液，10 mL/次，3次/d，尿管拔除后用生理鹽水與康復(fù)新液以1：10比例持續(xù)沖洗膀胱。兩組患者均在拔除尿管后3 d停藥。觀察兩組的臨床療效，比較兩組的膀胱功能改善情況、膀胱功能評(píng)分、臨床治療指標(biāo)。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為82.0%、96.0%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。與術(shù)后1 d比較，兩組術(shù)后2、3 d膀胱痙攣次數(shù)、持續(xù)時(shí)間、尿頻次數(shù)、尿急次數(shù)均顯著下降，且治療組術(shù)后1、2、3 d痙攣次數(shù)、持續(xù)時(shí)間、尿頻次數(shù)、尿急次數(shù)均顯著低于同期對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組VAS疼痛評(píng)分、OABSS評(píng)分、PPBC評(píng)分均顯著下降，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組膀胱功能評(píng)分明顯低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組膀胱沖洗、沖洗液轉(zhuǎn)清、留置導(dǎo)尿管時(shí)間均顯著短于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 康復(fù)新液聯(lián)合琥珀酸索利那新片治療前列腺電切術(shù)后膀胱痙攣具有較好的臨床療效，可改善臨床癥狀，促進(jìn)膀胱功能恢復(fù)，安全性較好，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the effect of Kangfuxin Liquid combined with Solifenacin Succinate Tablets in treatment of bladder spasm after prostatic electrocision. Methods Patients (100 cases) with bladder spasm after prostatic electrocision in Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine from January 2017 to January 2018 were randomly divided into control and treatment groups, and each group had 50 cases. Patients in the control group were po administered with Solifenacin Succinate Tablets after operation, 5 mg/time, once daily, after removal of catheter, continuous irrigation of the bladder with normal saline. Patients in the treatment group were po administered with Kangfuxin Liquid on the basis of the control group, 10 mL/time, three times daily, after removal of catheter, continuous irrigation of the bladder with normal saline and Kangfuxin Liquid (1:10). Patients in two groups were stopped taking medicine after removal of catheter for 3 d. After treatment, the clinical efficacies were evaluated, and the improvement of bladder function, the scores of bladder function, and the clinical treatment indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 82.0% and 96.0%, respectively, and there was difference between two groups (P<0.05). Comparison with 1 d after operation, frequency of spasm, duration of spasm, frequency of urination and number of urgency in two groups were significantly decreased at 2 and 3 d after operation, and the difference was statistically significant in the same group (P<0.05). And at 1, 2, and 3 d after operation, the observational indexes in the treatment group were significantly lower than those in the control group at the same time, with significant difference between two groups (P<0.05). After treatment, the scores of VAS, OABSS, and PPBC in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the time of bladder irrigation, rinse fluid, and indwelling catheter in the treatment group were significantly shorter than those in the control group, and there was difference between two groups (P<0.05). Conclusion Kangfuxin Liquid combined with Solifenacin Succinate Tablets has clinical curative effect in treatment of bladder spasm after prostatic electrocision, can improve clinical symptoms, and promot bladder function recovery, with good safety, which has a certain clinical application value.