目的 探索2015-2017年海安縣人民醫(yī)院感染性疾病病原菌的分布及耐藥性。方法 采用回顧性調(diào)查方法，對2015-2017年海安縣人民醫(yī)院病原菌分布及耐藥性進行統(tǒng)計學分析。結(jié)果 共分離出病原菌2 484株，檢出率為6.84%。醫(yī)院感染主要發(fā)生在傳染科、SICU、胸外科和神經(jīng)外科。分離病原菌中分離率較高的為大腸埃希菌、銅綠假單胞菌、肺炎克雷伯菌、鮑曼不動桿菌和金黃色葡萄球菌，其中大腸埃希菌在2015-2017年的分離率均為最高。主要病原菌的耐藥率從總體來看呈不斷上升的趨勢，其中大腸埃希菌、肺炎克雷伯菌以及銅綠假單胞菌對頭孢唑啉的耐藥率在2015-2017年均為100.00%。結(jié)論 海安縣人民醫(yī)院2015-2017年總體上病原菌檢出率逐漸升高，應引起感染科及其他相關部門的重視，嚴格控制抗菌藥物的使用。

Objective To explore the distribution and drug resistance of infectious diseases in Hai'an People's Hospital from 2015 to 2017. Methods A retrospective survey was conducted to analyze the distribution and drug resistance of pathogenic bacteria in Hai'an People's Hospital from 2015 to 2017. Results Total 2 484 strains of pathogens were isolated with the detection rate of 6.84%. Hospital infection mainly occurred in the Department of Infection, SICU, Thoracic Surgery, Neurosurgery, and Urology. Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococcus aureus had higher detection rate. And the detection rate of E. coli was the highest from 2015 to 2017. The drug resistance rate of main pathogenic bacteria had the trend of continuously increasing on the whole. The drug resistance rate of E. coli, K. pneumoniae, and P. aeruginosa against cefazolin were 100.00% from 2015 to 2017. Conclusion The drug resistance rate of main pathogenic bacteria has the trend of continuously increasing on the whole, which should be paid attention to during Department of Infection and other relevant departments, and the use of antibiotics should be controlled strictly.