目的 探討麝香保心丸聯(lián)合單硝酸異山梨酯緩釋片治療冠心病心絞痛的臨床療效。方法 選取2014年12月-2017年9月金堂縣中醫(yī)醫(yī)院收治的冠心病心絞痛患者106例，按照隨機數字表法將所有患者分為對照組和治療組，每組各53例。對照組口服單硝酸異山梨酯緩釋片，40 mg/次，1次/d。治療組在對照組治療的基礎上口服麝香保心丸，45 mg/次，3次/d。兩組患者均連續(xù)治療2個月。觀察兩組的臨床療效和心電圖療效，比較兩組的頸動脈內膜中層厚度（IMT）值和臨床癥狀。結果 治療后，對照組和治療組的臨床療效總有效率分別為75.5%、92.5%，兩組比較差異有統(tǒng)計學意義（P<0.05）。治療后，對照組和治療組的心電圖療效總有效率分別為75.5%、90.6%，兩組比較差異有統(tǒng)計學意義（P<0.05）。治療后，兩組頸動脈IMT值顯著降低，同組治療前后比較差異有統(tǒng)計學意義（P<0.05）；且治療組頸動脈IMT值明顯低于對照組，兩組比較差異具有統(tǒng)計學意義（P<0.05）。治療后，治療組心絞痛發(fā)作頻率、發(fā)作時長和硝酸甘油使用量明顯低于對照組，兩組比較差異具有統(tǒng)計學意義（P<0.05）。結論 麝香保心丸聯(lián)合單硝酸異山梨酯緩釋片治療冠心病心絞痛具有較好的臨床療效，能夠改善患者臨床癥狀，安全性較好，具有一定的臨床推廣應用價值。

Objective To investigate the effect of Shexiang Baoxin Pills combined with Isosorbide Mononitrate Sustained-release Tablets in treatment of angina pectoris of coronary heart disease. Methods Patients (106 cases) with angina pectoris of coronary heart disease in Jintang County Chinese Medicine Hospital from December 2014 to September 2017 were randomly divided into control and treatment groups, and each group had 53 cases. Patients in the control group were po administered with Isosorbide Mononitrate Sustained-release Tablets, 40 mg/time, once daily. Patients in the treatment group were po administered with Shexiang Baoxin Pills on the basis of the control group, 45 mg/time, three times daily. Patients in two groups were treated for 2 months. After treatment, the clinical efficacies and electrocardiogram efficacies were evaluated, and IMT values of arteria carotis and clinical symptoms in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 75.5% and 92.5%, respectively, and there was difference between two groups (P<0.05). After treatment, the electrocardiogram efficacies in the control and treatment groups were 75.5% and 90.6%, respectively, and there was difference between two groups (P<0.05). After treatment, IMT values of arteria carotis in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the IMT value of arteria carotis in the treatment group was significantly lower than that in the control group, with significant difference between two groups (P<0.05). After treatment, the frequency and duration of angina pectoris, and nitroglycerin usage in the treatment group were significantly lower than those in the control group (P<0.05). Conclusion Shexiang Baoxin Pills combined with Isosorbide Mononitrate Sustained-release Tablets has clinical curative effect in treatment of angina pectoris of coronary heart disease, can improve clinical symptoms, with good safety, which has a certain clinical application value.