目的 觀察小兒肺熱咳喘口服液聯(lián)合美洛西林鈉治療小兒肺炎的臨床療效。方法 選取2016年7月-2017年6月天津市西青醫(yī)院收治的106例小兒肺炎患兒，隨機(jī)分為對(duì)照組和治療組，每組各53例。對(duì)照組靜脈滴注注射用美洛西林鈉，0.1 g/（kg·d），3次/d；治療組在對(duì)照組治療基礎(chǔ)上口服小兒肺熱咳喘口服液，10 mL/次，4次/d。兩組均連續(xù)治療10 d。觀察兩組的臨床療效，比較兩組臨床癥狀體征改善情況。比較兩組治療前后C反應(yīng)蛋白（CRP）、白細(xì)胞介素-6（IL-6）水平的變化情況。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為83.02%、94.34%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組咳嗽消失時(shí)間、喘息消失時(shí)間、肺部啰音消失時(shí)間、退熱時(shí)間均顯著短于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組CRP、IL-6水平均顯著降低，同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，治療組CRP、IL-6水平顯著低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 小兒肺熱咳喘口服液聯(lián)合美洛西林鈉治療小兒肺炎具有較好的臨床療效，可迅速改善患者臨床癥狀體征，降低CRP、IL-6因子水平，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical curative effect of Xiaoer Feire Kechuan Oral Liquid combined with mezlocillin sodium in treatment of infantile pneumonia. Methods Children (106 cases) with infantile pneumonia in Tianjin Xiqing Hospital from July 2016 to June 2017 were randomly divided into control (53 cases) and treatment (53 cases) group. Patients in the control group were iv administered with Mezlocillin Sodium for injection, 0.1 g/(kg·d), three times daily. Patients in the treatment group were po administered with Xiaoer Feire Kechuan Oral Liquid, 10 mL/time, four times daily. Patients in two groups were treated for 10 d. After treatment, the clincial efficacies were evaluated, and the improvement of clinical symptoms and signs were compared between the two groups. After treatment, the changes of CRP and IL-6 in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group were 83.02% and 94.34%, and there were differences between two groups (P<0.05). After treatment, cough disappeared time, wheezing disappeared time, lung murmur disappeared time, and heat degenerative time in the treatment group were significantly shorter than those in the control group, and there were differences between two groups (P<0.05). After treatment, CRP and IL-6 in two groups were significantly decreased, and there were differences in the same group (P<0.05). After treatment, CRP and IL-6 in the treatment group were lower than those in the control group, and there were differences between two groups (P<0.05). Conclusion Xiaoer Feire Kechuan Oral Liquid combined with mezlocillin sodium has significant clinical effect in treatment of infantile pneumonia, and clinical symptoms and signs of patients can be improved rapidly, and can reduce the levels of CRP and IL-6, which has a certain clinical application value.