目的 探討銀杏達(dá)莫注射液聯(lián)合生長抑素治療急性胰腺炎的臨床效果。方法 選取2015年1月-2017年12月亳州市人民醫(yī)院收治的82例急性胰腺炎患者，隨機(jī)分為對(duì)照組和治療組，每組各41例。對(duì)照組持續(xù)微量泵入注射用生長抑素，以100 μg為首次劑量，靜脈推注，而后采取靜脈微量泵以50 μg/h維持。治療組在對(duì)照組治療基礎(chǔ)上靜脈滴注銀杏達(dá)莫注射液，20 mL加入500mL生理鹽水均勻混合后給藥，1次/d。兩組均連續(xù)治療7 d。觀察兩組的臨床療效，比較兩組血、尿淀粉酶（AMY）和血C反應(yīng)蛋白（CRP）恢復(fù)正常時(shí)間及腹痛、腹部壓痛消失時(shí)間。比較兩組血AMY、尿AMY活性、血小板平均體積（MPV）、C反應(yīng)蛋白（CRP）血清水平和改良CT嚴(yán)重指數(shù)（MCTSI）的變化情況。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為75.6%、92.7%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組血AMY、尿AMY及血CRP恢復(fù)正常時(shí)間，腹痛、腹部壓痛消失時(shí)間均顯著短于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組血AMY、尿AMY、MPV、CRP水平及MCTSI評(píng)分均較治療前顯著降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，治療組血AMY、尿AMY、MPV、CRP水平及MCTSI評(píng)分均顯著低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 銀杏達(dá)莫注射液聯(lián)合生長抑素治療急性胰腺炎具有較好的臨床療效，能有效緩解患者癥狀，改善血小板功能，減輕組織損傷，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical effects of Ginkgo Leaf Extract and Dipyridamole Injection combined with somatostatin in treatment of acute pancreatitis. Methods Patients (82 cases) with acute pancreatitis in the People's Hospital of Bozhou from January 2015 to December 2017 were randomly divided into control (41 cases) and treatment (41 cases) groups. Patients in the control group were continuously pumped with Somatostatin for injection, the first dosage was 100 μg for intravenous infusion, and then the intravenous micropump was 50 μg/h. Patients in the treatment group were iv administered with Ginkgo Leaf Extract and Dipyridamole Injection on the basis of the control group, 20 mL added to 500 mL normal saline and fully diluted, once daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and restored to normal time of blood, urine AMY and blood CRP and disappeared time of abdominal pain and abdominal tenderness in two groups were compared. The changes of blood AMY, urinary AMY, MPV, serum CRP and MCTSI in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group were 75.6% and 92.7%, and there were differences between two groups (P<0.05). After treatment, restored to normal time of blood, urine AMY and blood CRP and disappeared time of abdominal pain and abdominal tenderness in the treatment group were shorter than those in the control group, and there were differences between two groups (P<0.05). After treatment, blood AMY, urinary AMY, MPV, serum CRP and MCTSI in the two groups were significantly decreased, and there were differences in the same group (P<0.05). After treatment, blood AMY, urinary AMY, MPV, serum CRP and MCTSI in the treatment group were lower than those in the control group, and there were differences between two groups (P<0.05). Conclusion Ginkgo Leaf Extract and Dipyridamole Injection combined with somatostatin has significant clinical effect in treatment of acute pancreatitis, and can effectively alleviate symptoms, also can improve platelet function and reduce tissue damage, which has a certain clinical application value.