目的 探討甘珀酸鈉片聯(lián)合奧美拉唑腸溶膠囊治療消化性潰瘍的臨床療效。方法 選取2016年6月-2017年6月湖北醫(yī)藥學院附屬人民醫(yī)院收治的消化性潰瘍患者102例作為研究對象，采取隨機數字表法將所有患者分為對照組和治療組，每組各51例。對照組口服奧美拉唑腸溶膠囊，40 mg/次，2次/d。治療組在對照組治療的基礎上飯后口服甘珀酸鈉片，第1周80 mg/次，3次/d，之后50 mg/次，3次/d。兩組患者均連續(xù)治療4周。觀察兩組的臨床療效，比較兩組的潰瘍愈合時間、臨床癥狀消失時間。結果 治療后，對照組、治療組總有效率分別為84.31%、96.08%，兩組總有效率比較差異有統(tǒng)計學意義（P<0.05）。治療后，治療組十二指腸潰瘍、胃潰瘍、復合潰瘍愈合時間明顯短于對照組，兩組比較差異具有統(tǒng)計學意義（P<0.05）。治療后，治療組潰瘍痛、燒心、反酸消失時間均明顯短于對照組，兩組比較差異具有統(tǒng)計學意義（P<0.05）。結論 甘珀酸鈉片聯(lián)合奧美拉唑腸溶膠囊治療消化性潰瘍臨床療效顯著，能加快潰瘍面愈合，改善臨床癥狀，值得在臨床推廣應用。

Objective To investigate the effect of Carbenoxolone Sodium Tablets combined with Omeprazole Enteric-coated Capsules in treatment of pepti culcer. Methods Patients (102 cases) with peptic ulcer in Remin Hospital, Hubei University of Medicine from June 2016 to June 2017 were randomly divided into control and treatment groups, and each group had 51 cases. Patients in the control group were po administered with Omeprazole Enteric-coated Capsules after dinner, 40 mg/time, twice daily. Patients in the treatment group were po administered with Carbenoxolone Sodium Tablets on the basis of the control group, 80 mg/time, three times daily in the fist week, and then 50 mg/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical efficacy was evaluated, and the ulcer healing time and clinical symptoms disappeared times in two groups were compared. Results After treatment, the endoscopic efficacies in the control and treatment groups were84.31% and 96.08%, respectively, and there was difference between two groups (P<0.05). After treatment, healing times of duodenal ulcer, gastric ulcer and complex ulcer in the treatment group were significantly shorter than those in the control group, and there was difference between two groups (P<0.05). After treatment, the disappearance times of ulcerative pain, heart burning, and acid reacid were significantly shorter than those in the control group, and there was difference between two groups (P<0.05). Conclusion Carbenoxolone Sodium Tablets combined with Omeprazole Enteric-coated Capsules has clinical curative effect in treatment of pepti culcer, can accelerate the healing of ulcers, improve clinical symptoms, which has a certain clinical application value.