目的 對(duì)2017-2018年江蘇省中醫(yī)院腦梗死住院患者使用活血化瘀類中藥注射劑的合理性進(jìn)行分析，促進(jìn)合理使用。方法 采用回顧性分析的方法對(duì)江蘇省中醫(yī)院800例腦梗死的病歷進(jìn)行分析，調(diào)查活血化瘀類中藥注射劑的使用種類、適應(yīng)癥、用藥時(shí)機(jī)、用藥療程、用法用量、溶媒的選擇及溶媒量、聯(lián)合用藥情況以及使用時(shí)是否發(fā)生不良反應(yīng)，通過分析找出其使用不合理的地方，并提出相應(yīng)的整改措施。結(jié)果 共有11種活血化瘀類中藥注射劑用于腦梗死患者的輔助治療。使用率最高的活血化瘀類中藥注射劑為銀杏二萜內(nèi)酯葡胺注射液，使用率達(dá)34.68%。316例患者存在超適應(yīng)癥用藥，占39.50%。超療程使用占總使用頻次的1.91%。未按說明書推薦使用的稀釋溶媒有2.50%。聯(lián)合使用的治療腦梗死的相關(guān)藥物有17種。結(jié)論 江蘇省中醫(yī)院腦梗死住院患者的在活血化瘀類中藥注射劑的使用上存在一定的不合理用藥現(xiàn)象，需加強(qiáng)對(duì)活血化瘀類中藥注射劑在使用中的監(jiān)測(cè)和管理。

Objective To evaluate the rationality of traditional Chinese medicine injections for promoting blood circulation in patients with cerebral infarction in Jiangsu Province Hospital of Chinese Medicine from 2017 to 2018, to promote the use of traditional Chinese medicine injections for promoting blood circulation in patients with cerebral infarction. Methods A retrospective analysis method was used to analyze the 800 cases of cerebral infarction in Jiangsu Province Hospital of Chinese Medicine. The types of traditional Chinese medicine injections, indications, timing of medication, course of medication, usage and dosage, choice of solvent and amount of solvent, combination of drugs, and adverse drug reactions were evaluated to find out the unreasonable places and proposing corresponding corrective measures. Results There were 11 kinds of traditional Chinese medicine injections for the treatment of cerebral infarction. The highest utilization rate of Chinese medicine injection was Ginkgo Biloba Lactone Glucamine Injection with the utilization rate of 34.68%. There were 316 cases of super-instruction medication, accounting for 39.50%. The frequency of use of the super-treatment was 1.91%. The diluted solvent which was not recommended according to the instructions was 2.50%. There were 17 kinds of combined antithrombotic drugs. Conclusion There are some unreasonable drug use phenomenon of traditional Chinese medicine injections for promoting blood circulation in patients with cerebral infarction in Jiangsu Province Hospital of Chinese Medicine, and it is necessary to strengthen the monitoring and administration of clinical use of Chinese medicine injections.

R971

江蘇省藥學(xué)會(huì)-天晴醫(yī)院藥學(xué)基金資助項(xiàng)目（Q2018011）