新型冠狀病毒肺炎（COVID-19）于2019年12月在武漢爆發(fā)，目前尚無特效治療藥物，臨床治療以對癥治療、控制并發(fā)癥為主。國家衛(wèi)健委和多個省的診療方案中推薦藿香正氣用于COVID-19醫(yī)學觀察期乏力伴胃腸不適或臨床治療期"濕邪、寒濕、疫毒"相關(guān)中醫(yī)證型的治療。藿香正氣為常用的祛濕劑，有解表化濕、理氣和中的功效，主要從藥理研究和臨床研究方面綜述了藿香正氣的抗病毒、抗炎和改善相關(guān)癥狀等的研究進展，并嘗試探討了藿香正氣用于防治COVID-19的可能機制，以期為藿香正氣防治COVID-19的應用提供參考。

The coronavirus disease 2019 (COVID-19) firstly outbroke in Wuhan on December 2019. Currently, there is no specific treatment drug for COVID-19, and the main clinical treatments are symptom relieving and complication controlling. The treatment protocols of National Health Commission and several provinces recommend Huoxiang Zhengqi for the treatment of patients with fatigue and stomach uncomfortable in observation period or patients with "dampness pathogen, cold-dampness or epidemic toxin" relevant symptoms in clinical treatment period. Huoxiang Zhengqi is frequently-used damp-clearing prescription and have efficacy of reliving superficies, dispersing dampness, and harmonizing stomach. The perspective of pharmacology and clinical trials of Huoxiang Zhengqi in antivirus, anti-inflammation and relieving symptoms are reviewed in this paper, and the possible mechanism of Huoxiang Zhengqi in prevention and treatment of COVID-19 is discussed, hoping to provide reference for applying Huoxiang Zhengqi in prevention and treatment of COVID-19.

R286.4

國家“重大新藥創(chuàng)制”科技重大專項（2017ZX09301005）