目的 對西安醫(yī)學(xué)院附屬寶雞醫(yī)院排名前10位的輔助用藥重點監(jiān)控品種的使用情況進行分析，為加強輔助用藥的監(jiān)管和促進臨床合理用藥提供參考。方法 通過醫(yī)院信息系統(tǒng)將2018年重點監(jiān)控藥品的科室分布、銷售金額、用藥頻度（DDDs）、日均費用（DDC）和藥品排序比（B/A）進行統(tǒng)計分析，并對其使用合理性進行醫(yī)囑點評分析。結(jié)果 重點監(jiān)控品種使用科室大多與其科室疾病譜相符。銷售金額排序前3位依次為小牛血清去蛋白注射液、丹參川芎嗪注射液和醒腦靜注射液；按DDDs排序前3位依次為丹參川芎嗪注射液、小牛血清去蛋白注射液、腺苷鈷胺注射液；按DDC排序前3位依次為醒腦靜注射液、小牛血清去蛋白注射液、轉(zhuǎn)化糖電解質(zhì)注射液；鹿瓜多肽注射液、注射用硫辛酸、舒血寧注射液和注射用血栓通的B/A接近1。不合理應(yīng)用集中表現(xiàn)在適應(yīng)癥不適宜、給藥劑量不規(guī)范，構(gòu)成比分別為59.41%、16.01%。結(jié)論 西安醫(yī)學(xué)院附屬寶雞醫(yī)院重點監(jiān)控藥品管理工作初見成效，但仍需采取積極有效的監(jiān)管措施進一步促進重點監(jiān)控藥品的合理使用。

Objective To investigate the utilization of key monitoring varieties among the top 10 adjuvant drugs in Affiliated Baoji Hospital of Xi' an Medical University, and provide references for reinforcing the supervision and management for adjuvant drugs and promoting rational clinical use of drugs. Methods The drug information management system was used to collect the department distribution, sales amount, frequency of drug use (DDDs), defined daily cost (DDC), and the drug sequence ratio (B/A) of key monitoring drugs in 2018. And the rationality of their use was analyzed. Results The department distribution of key monitoring varieties were in line with their disease spectrum. Sales amounts of Deproteinised Calf Blood Serum Injection, Danshen Chuanxiongqin Injection, and Xingnaojing Injection were ranked the top three. DDDs of Chuanxiongqin Injection, Deproteinised Calf Blood Serum Injection, and Adenosine Cobalamin Injection were ranked the top three. DDC of Xingnaojing Injection, Deproteinised Calf Blood Serum Injection, and Invert Sugar and Electrolytes Injection were ranked the top three. B/A of Cervus and Cucumis Polypeptide Injection, Thioctic Acid for injection, Shuxuening Injection, and Xueshuantong for injection were close to 1. After the intervention, the sales amount and amount of usage of those key monitoring varieties among adjuvant drugs decreased. The clinical irrational utilization of adjuvant drugs mainly manifested as inappropriate indications and nonstandard dosing, accounting for 59.41% and 16.01%. Conclusion The supervising of key monitoring medicines has achieved certain results in Affiliated Baoji Hospital of Xi'an Medical University, and positive and effective measures are needed to supervise the irrational use of drugs and promote the rational drugs use.

R969.3