目的 分析2015—2019年天津市眼科醫(yī)院局部抗青光眼藥品的使用情況及發(fā)展趨勢(shì)。方法 對(duì)天津市眼科醫(yī)院2015—2019年局部抗青光眼藥品的銷售金額、用藥頻度（DDDs）、日均費(fèi)用（DDC）、排序比（B/A）等進(jìn)行回顧性統(tǒng)計(jì)分析。結(jié)果 前列腺素衍生物類局部抗青光眼藥品的銷售金額遠(yuǎn)高于其他4類藥品銷售金額。拉坦前列素滴眼液（國(guó)產(chǎn)）、拉坦前列素滴眼液（進(jìn)口）、曲伏前列素滴眼液、鹽酸卡替洛爾滴眼液、酒石酸溴莫尼定滴眼液、布林佐胺滴眼液穩(wěn)居本院用藥金額前6位。鹽酸卡替洛爾滴眼液DDD穩(wěn)居第1位。除了2015—2016年鹽酸卡替洛爾滴眼液的DDC值略有上升外，其他滴眼液的DDC值均維持不變或呈下降的趨勢(shì)。鹽酸卡替洛爾滴眼液的B/A最高。結(jié)論 本院局部抗青光眼藥品使用基本合理，前列腺素衍生物類藥物逐漸成為抗青光眼的一線用藥。

Objective To analyze the use and development trend of local anti-glaucoma drugs in Tianjin Eye Hospital from 2015 to 2019. Methods The sales amount, drug frequency (DDDs), average daily cost (DDC), and ranking ratio (B/A) of local anti-glaucoma drugs in Tianjin Eye Hospital from 2015 to 2019 were statistically analyzed. Results The sales amount of prostaglandin local anti-glaucoma drugs was much higher than that of other four drugs. Ratanprost eye drops (domestic), ratanprost eye drops (imported), triprost eye drops, cateolol hydrochloride eye drops, bromomonidine tartrate eye drops, and brinzolamine eye drops were in the top 6 of sales amount. DDD of catarrhalol hydrochloride eye drops ranked first. Except for the DDC value of catarral hydrochloride eye drops increased slightly from 2015 to 2016, the DDC value of other eye drops remained unchanged or showed a downward trend. Catarrhhalol hydrochloride eye drops had the highest B/A. Conclusion The use of local anti-glaucoma drugs in Tianjin Eye Hospital is reasonable, and prostaglandin derivatives have gradually become the first-line anti glaucoma drugs.

R988.1