目的 對(duì)西安國(guó)際醫(yī)學(xué)中心醫(yī)院麻醉性鎮(zhèn)痛藥的臨床應(yīng)用情況進(jìn)行分析，為醫(yī)療機(jī)構(gòu)麻醉性鎮(zhèn)痛藥的規(guī)范化管理和臨床合理用藥提供參考和依據(jù)。方法 采用回顧性分析方法，從醫(yī)院管理信息系統(tǒng)（HIS）中調(diào)取2019年9月-2020年9月全院麻醉性鎮(zhèn)痛藥的使用數(shù)據(jù)，對(duì)其消耗量、使用金額、用藥頻度（DDDs）、限定日費(fèi)用（DDC）、排序比（B/A）和各專(zhuān)科醫(yī)院使用量等進(jìn)行統(tǒng)計(jì)分析。結(jié)果 鹽酸羥考酮緩釋片（10 mg）、鹽酸羥考酮緩釋片（40 mg）的消耗量位居前2位。注射用鹽酸瑞芬太尼（1 mg）、枸櫞酸舒芬太尼注射液的使用金額、DDDs均位居前2位，且B/A均等于1.00，其使用金額與用藥頻度同步性良好，經(jīng)濟(jì)效益與社會(huì)效益一致。芬太尼透皮貼劑（4.2 mg）日均費(fèi)用最低，患者經(jīng)濟(jì)負(fù)擔(dān)較小。鹽酸氫嗎啡酮注射液日均費(fèi)用最高，患者經(jīng)濟(jì)負(fù)擔(dān)較大。本院麻醉性鎮(zhèn)痛藥的使用量位居前3位的機(jī)構(gòu)依次是腫瘤醫(yī)院、麻醉手術(shù)中心和胸科醫(yī)院。腫瘤醫(yī)院麻醉性鎮(zhèn)痛藥使用量占全院總使用量的49.54%。結(jié)論 西安國(guó)際醫(yī)學(xué)中心醫(yī)院麻醉性鎮(zhèn)痛藥品規(guī)齊全，能夠滿(mǎn)足臨床需求，應(yīng)用基本合理。

Objective To analyze the clinical application of narcotic analgesics in Xi'an International Medical Center Hospital, to provide reference and basis for the standardized management and rational clinical use of narcotic analgesics. Methods By retrospective survey, the utilization of narcotic analgesics in the hospital during September 2019-September 2020 from HIS were extracted, and the usage, consumption sum, defined daily doses (DDDs), defined daily cost (DDC), drug sequence ratio (B/A) and the use amount of various specialized hospital were analyzed statistically. Results The consumption amount of Oxycodone Hydrochloride Prolonged-release Tablets (10 mg, 40 mg) ranked the top two. The consumption sum and DDDs of Remifentanil Hydrochloride for injection and Sufentanil Citrate Injetion ranked the first 2 places, the value of B/A were 1.00. The consumption sum and drug frequency had good synchronization, and the economic benefit was consistent with the social benefit. The average daily cost of fentanyl transdermal patch (4.2 mg) was the lowest, and the financial burden of patients was relatively small. On the contrary, the daily cost of hydromorone hydrochloride injection was the highest. The use of narcotic analgesics ranked the top three, in sequences, were the tumor hospital, the anesthesia operation center and the chest hospital. The use of narcotic analgesics in tumor hospitals accounted for 49.54% of the total usage of the hospital. Conclusion The variety and dosage form of narcotic analgesics in Xi'an International Medical Center hospital could meet the clinical needs and their applications were basically reasonable.

R971

廣西教育廳科研項(xiàng)目（2017KY0346）