目的 探討喜炎平注射液聯(lián)合頭孢西丁治療急性扁桃體炎的臨床療效。方法 選取柞水縣中醫(yī)醫(yī)院內(nèi)科門(mén)診2019年10月—2020年7月收治的60例急性扁桃體炎患者，采用照隨機(jī)數(shù)字表法分為對(duì)照組和治療組，每組各30例。對(duì)照組靜脈滴注注射用頭孢西丁鈉，4 g溶于250 mL生理鹽水，1次/d。治療組在對(duì)照組治療基礎(chǔ)上靜脈滴注喜炎平注射液，10 mL溶于5%葡萄糖溶液100 mL中，1次/d。兩組均連續(xù)治療2～5 d。觀察兩組的臨床療效，比較兩組臨床癥狀緩解時(shí)間、感染性相關(guān)指標(biāo)。結(jié)果 治療后，治療組總有效率是96.7%，顯著高于對(duì)照組的83.3%（P<0.05）。治療后，治療組咽痛、發(fā)熱惡寒、頭痛頭暈、鼻塞流涕等臨床癥狀改善時(shí)間明顯短于對(duì)照組（P<0.05）。治療后，兩組患者白細(xì)胞計(jì)數(shù)（WBC）、中性粒細(xì)胞、高敏C反應(yīng)蛋白（hs-CRP）均較治療前顯著降低（P<0.05）；且治療后治療組炎癥指標(biāo)顯著低于對(duì)照組（P<0.05）。結(jié)論 喜炎平注射液聯(lián)合頭孢西丁治療急性扁桃體炎具有較好的臨床療效，可以顯著縮短患者臨床癥狀緩解時(shí)間，降低感染性相關(guān)指標(biāo)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical efficacy of Xiyanping Injection combined with cefoxitin in treatment of acute tonsillitis. Methods A total of 60 patients with acute tonsillitis admitted to the internal medicine department of Zhashui County Hospital of Traditional Chinese Medicine from October 2019 to July 2020 were selected and divided into control group and treatment group by random number table method, with 30 patients in each group. Patients in the control group were iv administered with Cefoxitin Sodium for injection, 4 g was dissolved in 250 mL normal saline, once daily. Patients in the treatment group were iv administered with Xiyanping Injection on the basis of the control group, 10 mL was dissolved in 100 mL 5% glucose solution, once daily. Both groups were treated continuously for 2 — 5 d. The clinical efficacy of the two groups was observed, and the clinical symptom remission time and related indexes of infection were compared between the two groups. Results After treatment, the total effective rate of the treatment group was 96.7%, which was significantly higher than that of the control group (83.3%, P < 0.05). After treatment, the improvement time of clinical symptoms such as sore throat, fever and cold, headache and dizziness, nasal congestion, and runny nose in the treatment group was significantly shorter than that in the control group (P < 0.05). After treatment, the white blood cell count (WBC), neutrophils, and high-sensitivity C-reactive protein (hs-CRP) in two groups were significantly decreased compared with before treatment (P < 0.05). After treatment, inflammatory indexes in the treatment group were significantly lower than those in the control group (P < 0.05). Conclusion Xiyanping Injection combined with cefoxitin has a good clinical effect in treatment of acute tonsillitis, and can significantly shorten the time of clinical symptom remission, reduce the relevant indicators of infection, which has a certain value of clinical promotion and application.

R987

南京市中醫(yī)藥青年人才培養(yǎng)計(jì)劃項(xiàng)目（ZYQ20065）