目的 觀察豨薟通栓膠囊聯(lián)合長春西汀片治療腦梗死恢復(fù)期的臨床療效。方法 選取2019年3月—2021年2月開封市中心醫(yī)院收治的150例腦梗死恢復(fù)期患者，采用隨機數(shù)字表法將患者分為對照組和治療組，每組各75例。對照組飯后0.5 h口服長春西汀片，1片/次，3次/d。治療組在對照組基礎(chǔ)上飯后0.5 h口服豨薟通栓膠囊，3粒/次，3次/d。兩組患者均連續(xù)治療3個月。觀察兩組療效，比較兩組患者神經(jīng)功能缺損情況、日常生活活動能力、腦血流動力學(xué)參數(shù)、血液流變學(xué)。結(jié)果 治療后，治療組的總有效率為90.67%，高于對照組的總有效率74.67%，差異有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組美國國立衛(wèi)生研究院腦卒中量（NIHSS）評分較治療前降低，Barthel指數(shù)較治療前升高（P<0.05），且治療組的NIHSS評分、Barthel指數(shù)改善效果更明顯（P<0.05）。治療后，兩組阻力指數(shù)（RI）、搏動指數(shù)（PI）較治療前降低，平均血流速度（V_m）較治療前升高（P<0.05），且治療組的腦血流動力學(xué)參數(shù)改善效果更明顯（P<0.05）。治療后，兩組纖維蛋白原、血漿比黏度、D-二聚體較治療前降低（P<0.05），治療組的纖維蛋白原、血漿比黏度、D-二聚體均明顯低于對照組（P<0.05）。結(jié)論 豨薟通栓膠囊聯(lián)合長春西汀片治療腦梗死恢復(fù)期的療效較好，可提高患者日常生活能力，減輕腦神經(jīng)功能缺損，進一步改善腦血流動力學(xué)參數(shù)和血液流變學(xué)，具有一定的臨床應(yīng)用價值。

Objective To observe the clinical effect of Xixian Tongshuan Capsules combined with Vinpocetine Tablets in treatment of convalescence of cerebral infarction. Methods Patients (150 cases) with convalescence of cerebral infarction in Kaifeng Central Hospital from March 2019 to February 2021 were randomly divided into control and treatment groups, and each group had 75 cases. Patients in the control group were po administered with Vinpocetine Tablets at half an hour after dinner, 1 tablet/time, three times daily. Patients in the treatment group were po administered with Xixian Tongshuan Capsules at half an hour after dinner on the basis of the control group, 3 grains/time, three times daily. Patients in two groups were treated for 3 months. After treatment, the clinical efficacies were evaluated, and the neurological deficit, activities of daily living, cerebral hemodynamic parameters, hemorheology in two groups were compared. Results After treatment, the total effective rate of the treatment group was 90.67%, which was higher than that of the control group (74.67%), and the difference was statistically significant (P < 0.05). After treatment, the NIHSS score and Barthel index in two groups were lower than those before treatment (P < 0.05). After treatment, the fibrinogen, plasma specific viscosity, and D-dimer in two groups were lower than those before treatment (P < 0.05), and the fibrinogen, plasma specific viscosity, and D-dimer in the treatment group were significantly lower than those in the control group (P < 0.05). Conclusion Xixian Tongshuan Capsules combined with Vinpocetine Tablets has clinical curative effect in treatment of convalescence of cerebral infarction, can improve the ability of daily living, reduce the defect of cerebral nerve function, and further improve the parameters of cerebral hemodynamics and hemorheology, which has a certain clinical value.

R971

河南省醫(yī)學(xué)科技攻關(guān)計劃聯(lián)合共建立項項目（LHGJ202000839）