1.2。結(jié)論 南京醫(yī)科大學(xué)附屬腦科醫(yī)院第二類精神藥品結(jié)構(gòu)合理,非苯二氮類藥物使用逐漸增多。;Objective To evaluate the application situation and development tendency of the second class psychotropic drugs in the Affiliated Brain Hospital of Nanjing Medical University from 2017 to 2020. Methods Using the consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) as the indicators, to retrospectively analyze the application of the second class psychotropic drugs. Results The second class psychotropic drugs were classified according to chemical structure, and the sum composition ratio of each category was basically stable. The proportion of barbiturates was the lowest, and the consumption sum of benzodiazepines and non-benzodiazepines increased year by year. The DDDs composition ratio of non-benzodiazepines showed a slight increase trend, while that of benzodiazepines and barbiturates showed a slight decrease trend. The top 3 of consumption sum of the second class psychotropic drugs remained stable, namely, zolpidem, lorazepam and zopiclone. The DDDs of zolpidem, zopiclone and lorazepam were always in the top 3. DDC of the second class psychotropic drugs remained basically stable and increased slightly from 2017 to 2020. The B/A of most drugs ranged from 0.8 to 1.2, with the B/A of oxazepam < 0.8, and the B/A of estazolam, alprazolam and nitrazepam > 1.2. Conclusion The application structure of the second class psychotropic drugs is basically reasonable, and the use of non-benzodiazepines is increasing gradually."/>