目的 調(diào)查分析天津市海河醫(yī)院收治的新型冠狀病毒肺炎（COVID-19）確診患者的臨床分型及用藥情況，為COVID-19抗病毒治療藥物的合理使用提供參考。方法 收集天津市海河醫(yī)院2020年1月21日—2021年1月21日COVID-19患者抗病毒用藥的銷(xiāo)售量、銷(xiāo)售金額等對(duì)用藥頻度（DDDs）、日均費(fèi)用（DDC）、排序比（B/A）等指標(biāo)進(jìn)行統(tǒng)計(jì)分析。調(diào)查患者臨床分型及抗病毒藥物的使用方法，參考《新型冠狀病毒肺炎診療方案》，評(píng)估抗病毒藥物使用的合理性。結(jié)果 α2b干擾素銷(xiāo)售金額最高、DDC最高、重型使用率最高；鹽酸阿比多爾DDDs排序最高、藥品排序比（B/A）比值>1，輕型、普通型、危重型使用率最高。經(jīng)調(diào)查，醫(yī)院抗病毒用藥傾向于早期治療。存在同時(shí)應(yīng)用3種抗病毒藥物和療程>10 d的病例。結(jié)論 天津市海河醫(yī)院以鹽酸阿比多爾口服聯(lián)合α2b干擾素霧化吸入構(gòu)成基本用藥?？共《舅幬锸褂寐逝c臨床分型密切相關(guān)。醫(yī)院完全按照當(dāng)時(shí)發(fā)行的《新型冠狀病毒肺炎診療方案》的規(guī)定使用抗病毒藥物并對(duì)抗病毒藥物使用密切觀察耐藥性和不良反應(yīng)的發(fā)生。

Objective To investigate and analyze the clinical classification and medication status of confirmed COVID-19 patients admitted to Tianjin Haihe Hospital, providing reference for rational use of antiviral drugs for COVID-19.Method The sales volume and consumption sum of antiviral drugs for COVID-19 patients in Tianjin Haihe Hospital from January 21, 2020 to January 21, 2021 were collected for statistical analysis of DDDs, DDC, B/A and other indicators. Investigate the clinical classification of patients and the use of antiviral drugs, and evaluate the rationality of the use of antiviral drugs by referring to the COVID-19 Diagnosis and Treatment Protocol. Results The sales amount of interferon α2b was the highest, the DDC was the highest, and the heavy-duty usage rate was the highest. The DDDs of Arbidol hydrochloride was the highest, the drug sequencing ratio (B/A) ratio was > 1, and the utilization rate of light, general and critical type was the highest. After investigation, the hospital's antiviral drugs tend to be treated early. There are cases of simultaneous application of 3 antiviral drugs and a course of treatment > 10 d. Conclusion The hospital uses arbidol hydrochloride orally combined with α2b interferon nebulized inhalation to constitute the basic medication. The use rate of antiviral drugs is closely related to clinical classification. The hospital used antiviral drugs in accordance with the COVID-19 Diagnosis and Treatment Plan issued at that time and used antiviral drugs to closely observe the occurrence of drug resistance and adverse reactions.

R978.7