目的 分析2019—2020年天津市寶坻區(qū)人民醫(yī)院Ⅰ類切口手術(shù)圍手術(shù)期預(yù)防性應(yīng)用抗菌藥物現(xiàn)狀，為提高圍手術(shù)期抗菌藥物合理使用提供參考依據(jù)。方法 從天津市寶坻區(qū)醫(yī)院信息系統(tǒng)中調(diào)取2019年1月1日—2020年12月31日Ⅰ類切口手術(shù)出院患者病歷10 507例，對(duì)圍手術(shù)期預(yù)防用藥情況進(jìn)行分析，每月隨機(jī)抽樣50份病歷進(jìn)行專項(xiàng)點(diǎn)評(píng)，總結(jié)點(diǎn)評(píng)情況。結(jié)果 10 507例Ⅰ類切口手術(shù)患者中，2 375例預(yù)防性使用抗菌藥物，抗菌藥物預(yù)防性使用率為22.60%；使用率最高的科室為骨科（42.04%），使用率最低的科室為泌尿外科（1.24%）；抗菌藥物品種選擇排名第一的為頭孢唑林鈉，構(gòu)成比為86.32%；用藥療程≤24 h的有1 821例（占76.67%），>48 h的有106例（占4.47%）；抽樣點(diǎn)評(píng)1 200例Ⅰ類切口患者病歷，合理用藥1 185例（占98.75%），不合理用藥15例（占1.25%），主要涉及療程不適宜（超過24 h且無理由，占比46.67%）、品種不適宜（占比40.00%）。結(jié)論 天津市寶坻區(qū)人民醫(yī)院Ⅰ類切口手術(shù)圍手術(shù)期預(yù)防性應(yīng)用抗菌藥物的使用基本合理。

Objective To analyze the usage of prophylactic antibiotiscs in perioperative period of type Ⅰ incision in Tianjin Baodi Hospital from January 1, 2019 to December 31, 2020, so as to provide reference for improving the rational use of perioperative antibiotics. Methods A total of 10 507 medical records of discharged patients with type I incision surgery from 2019 to 2020 were collected from the Tianjin Baodi Hospital information system. The preventive medication and rational administration were analyzed. 50 medical records were randomly sampled every month to review and summarize the comments. Results Among 10 507 patients of type Ⅰ incision surgery, 2 375 patients were prophylaxis with antibiotics, and the rate of prophylactic use of antibiotics was 22.60%. The department of orthopedics had the highest utilization rate (42.04%), and the department of urology had the lowest utilization rate (1.24%). The first antibacterial variety was cefazolin sodium, and the composition ratio was 86.32%. There were 1 821 cases (76.67%) whose medication course was less than 24 h, and 106 cases (4.47%) whose medication course was > 48 h. Among 1 200 patients with type I incision, 1 185 cases (98.75%) were used rationally, and 15 cases (1.25%) were used irratively, mainly involving unsuitable course of treatment (more than 24 hours without reason, 46.67%), and unsuitable type (40.00%). Conclusion The prophylactic application of antibiotics in type Ⅰ incision in Tianjin Baodi Hospital is basically rational.

R978.1