目的 統(tǒng)計青島市精神衛(wèi)生中心2019—2021年第二類精神藥品使用情況并分析變化趨勢，為臨床合理用藥提供參考。方法 采用回顧性分析方法統(tǒng)計青島市精神衛(wèi)生中心信息系統(tǒng)中2019年1月—2021年12月第二類精神藥品的銷售金額，并計算藥品用藥頻度（DDDs）、限定日費用（DDC）以及藥品排序比（B/A）。結(jié)果 2019—2021年，醫(yī)院第二類精神藥品銷售金額呈逐年增長趨勢，奧沙西泮片和佐匹克隆片的銷售金額排序始終居于前2位；第二類精神藥品的DDDs總體呈增長趨勢，佐匹克隆片、氯硝西泮片、阿普唑侖片的DDDs排序始終居于前3位；第二類精神藥品的DDC及排序基本穩(wěn)定，其中奧沙西泮片、地西泮注射液的DDC較高，居于前2位；苯巴比妥片、地西泮片、勞拉西泮片（1 mg）、佐匹克隆片的B/A值接近于1.0。結(jié)論 青島市精神衛(wèi)生中心第二類精神藥品的使用基本合理，后期仍需加強監(jiān)督管理，以保證患者合理用藥。

Objective The use of category II psychotropic drugs in Qingdao Mental Health Center from 2019 to 2021 was analyzed, and the trend was analyzed, providing reference for rational drug use in clinic. Methods The consumption sum of category II psychotropic drugs from January 2019 to December 2021 in the information system of Qingdao Mental Health Center was analyzed retrospectively, and DDDs, DDC and B/A were calculated. Results From 2019 to 2021, the consumption sum of category II psychotropic drugs in hospitals increased year by year, and the consumption sum of Oxazepam Tablets and Zopicalone Tablets always ranked first and second. The DDDs of the second category of psychotropic drugs showed an increasing trend, and the DDDs of Zopiclone Tablets, Clonazepam Tablets, and Alprazolam Tablets always ranked the first 3. The DDC and order of the second type of psychotropic drugs were basically stable, among which the DDC of Oxazepam Tablets and Diazepam Injection were higher, ranking first and second. The B/A values of Phenobarbital Tablets, Diazepam Tablets, Lorazepam Tablets (1 mg) and Zopiclone Tablets were close to 1.0. Conclusion The use of class II psychotropic drugs in Qingdao Mental Health Center was basically reasonable, and supervision and management should be strengthened in the later stage to ensure rational drug use by patients.

R971