綠茶中的活性成分已經(jīng)被證明具有預防和控制癌癥的作用，其中表沒食子兒茶素沒食子酸酯（EGCG）抗癌活性最高。EGCG能夠通過調控氧化應激、阻滯腫瘤細胞周期、抑制腫瘤血管形成、誘導腫瘤細胞凋亡等途徑實現(xiàn)抗腫瘤效果。因此對EGCG抗腫瘤作用機制的進行了綜述，以期為EGCG的臨床應用提供參考。

The active ingredients in green tea have been proved to have anticancer effects, and (-)-epigallocatechin gallate (EGCG) had the highest anticancer activity. EGCG could achieve anticancer effects by regulating oxidative stress, blocking tumor cell cycle, inhibiting tumor angiogenesis, and inducing cancer cell apoptosis. This article reviews the mechanism of anticancer action of EGCG in order to provide reference for its clinical application.

R979.1

省部共建食品營養(yǎng)與安全國家重點實驗室開放課題（20210829）