乳腺癌是最常見的癌癥之一,屬于典型的異質性惡性腫瘤,臨床結局不佳。雙氫青蒿素是青蒿素在體內的主要代謝產(chǎn)物,可抑制乳腺癌腫瘤細胞增殖、促進腫瘤細胞凋亡、阻止腫瘤細胞轉移、誘導細胞自噬,因此對雙氫青蒿素抗乳腺癌的作用機制進行總結,希望為雙氫青蒿素的臨床使用提供參考。

Breast cancer, one of the most common cancers, is a typical heterogeneous malignancy with poor clinical outcome.Dihydroartemisinin is the main metabolite of artemisinin in vivo. Dihydroartemisinin can inhibit the proliferation of breast cancer tumor cells, promote tumor cell apoptosis, prevent tumor cell metastasis, and induce autophagy. This article summarizes the mechanism of dihydroartemisinin against breast cancer, hoping to provide reference for the clinical use of dihydroartemisinin.

R979.1

河北省中醫(yī)藥管理局科研計劃項目(2019005)