感染性肺炎已成為重大的全球健康問題,抗感染是臨床治療感染性肺炎最主要的治療方式。黃芩素是黃芩中的黃酮類成分,具有多種活性,可減輕病原微生物感染介導的炎癥反應,抑制多種炎癥因子的分泌,直接抗病毒和協(xié)同抗病毒作用,抗細胞凋亡,促進肺上皮細胞修復減輕肺部病理損傷?？偨Y(jié)了黃芩素防治感染性肺炎的作用機制,為指導黃芩素的臨床使用提供參考。

Infectious pneumonia has become a major global health issue, and anti-infection is the most important treatment for infectious pneumonia in clinical practice. Baicalin is a flavonoid component from Scutellariae Radix, which has various activities. Baicalin can reduce the inflammatory reaction mediated by pathogenic microorganism infection, inhibit the secretion of various inflammatory factors, directly and cooperatively antiviral effect, anti-apoptosis, promote the repair of pulmonary epithelial cells and reduce pathological damage to the lungs. This article summarized the mechanism of baicalin in prevention and treatment of infectious pneumonia, providing a reference for guiding the clinical use of baicalin.

R974

重慶市科衛(wèi)聯(lián)合醫(yī)學科研項目(2019ZDXM042)