草烏甲素具有良好的鎮(zhèn)痛作用，用于多種疼痛的治療。草烏甲素可作用于疼痛感知通路中的多個(gè)位點(diǎn)，發(fā)揮外周、中樞及其他鎮(zhèn)痛機(jī)制。草烏甲素的臨床治療涉及到骨關(guān)節(jié)疼痛、癌性疼痛、帶狀皰疹相關(guān)性疼痛、急性疼痛和其他疼痛。對(duì)草烏甲素的鎮(zhèn)痛機(jī)制和治療各類疼痛的臨床應(yīng)用進(jìn)行綜述，以期對(duì)草烏甲素的臨床治療提供參考。

Bulleyaconitine A has good analgesic effects and is used for treatment of various types of pain. Bulleyaconitine A can act on multiple targets in the pain perception pathway, playing a role in peripheral, central, and other analgesic mechanisms. The clinical treatment of bulleyaconitine A involves joint pain, cancer pain, herpes zoster associated rash pain, acute pain, etc. This article reviews the analgesic mechanism and clinical application of bulleyaconitine A in treatment of various types of pain, in order to provide reference for the clinical treatment of bulleyaconitine A.

R285

貴州省科技計(jì)劃項(xiàng)目(黔科合基礎(chǔ)-ZK[2023]一般389)