帕金森病已成為威脅老年人身心健康的主要疾病之一。紅景天苷是從紅景天中提取的主要活性化合物之一，具有多種藥理作用。紅景天苷可通過抑制細(xì)胞凋亡、增強(qiáng)細(xì)胞自噬、降低氧化應(yīng)激反應(yīng)、降低炎癥反應(yīng)、促進(jìn)膠質(zhì)細(xì)胞源性神經(jīng)營養(yǎng)因子的表達(dá)、提高多巴胺轉(zhuǎn)運(yùn)蛋白的表達(dá)以達(dá)到防治帕金森病的作用?？偨Y(jié)了紅景天苷防治帕金森病的藥理作用及其作用機(jī)制，為紅景天苷的臨床使用提供參考。

Parkinson's disease has become one of the main diseases threatening the physical and mental health of the elderly. Salidroside is one of the main active compounds from Rhodiolae Crenulatae Radix et Rhizoma, and has various pharmacological effects. Salidroside can prevent and treat Parkinson's disease by inhibiting cell apoptosis, enhancing autophagy, reducing oxidative stress, reducing inflammation, promoting the expression of GDNF, and increasing the expression of dopamine transporter. This article summarizes the pharmacological effects and their mechanisms of salidroside in the prevention and treatment of Parkinson's disease, providing evidence for the clinical use of salidroside.

R971