目的 探討新血寶膠囊聯(lián)合多維鐵口服溶液治療妊娠期缺鐵性貧血的臨床療效。方法 選取2021年6月—2023年6月在廣州市婦女兒童醫(yī)療中心柳州醫(yī)院治療的妊娠期缺鐵性貧血患者124例，隨機分為對照組（62例）和治療組（62例）。對照組患者口服多維鐵口服溶液，15 mL/次，2次/d。治療組患者在對照組基礎上口服新血寶膠囊，2 粒/次，3次/d。兩組患者連續(xù)治療4周。觀察兩組患者臨床療效，比較治療前后兩組患者血紅蛋白（Hb）、平均血紅蛋白含量（MCH）、平均血紅蛋白濃度（MCHC）、鐵蛋白和總鐵結(jié)合力（TIBC）水平。結(jié)果 治療后，治療組總有效率為96.77%，明顯高于對照組的87.10%（P＜0.05）。治療后，兩組Hb、MCH、MCHC和鐵蛋白水平較治療明顯升高，而TIBC水平明顯降低（P＜0.05），且治療組這些指標水平明顯好于對照組（P＜0.05）。結(jié)論 新血寶膠囊聯(lián)合多維鐵口服溶液治療妊娠期缺鐵性貧血具有較好的臨床療效，可顯著改善患者的貧血指標和鐵代謝指標，且不良反應少。

Objective To explore the efficacy of Xinxuebao Capsules and Multivitamin Iron Oral Solution in treatment of iron deficiency anemia during pregnancy. Methods Patients (124 cases) with iron deficiency anemia during pregnancy in Guangzhou Women and Children's Medical Center Liuzhou Hospital from June 2021 to June 2023 were randomly divided into control (62 cases) and treatment (62 cases) group. Patients in the control group were po administered with Multivitamin Iron Oral Solution, 15 mL/time, twice daily. Patients in the treatment group were po administered with Xinxuebao Capsules on the basis of the control group, 2 grains/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical evaluations was evaluated, the levels of Hb, MCH, MCHC, ferritin and TIBC in two groups before and after treatment were compared. Results After treatment, the clinical effective rate of the treatment group was 96.77%, which was significantly higher than that of the control group (87.10%, P＜0.05). After treatment, the levels of Hb, MCH, MCHC and ferritin in two groups were significantly higher than those in the treatment group, while the level of TIBC was significantly decreased in two groups (P＜0.05), and the level of these indexes in the treatment group was significantly better than that in the control group (P＜0.05). Conclusion Xinxuebao Capsules combined with Multivitamin Iron Oral Solution has a good clinical effect in the treatment of iron deficiency anemia during pregnancy, which can significantly improve the anemia index and iron metabolism index with less adverse reactions.

R973

廣西壯族自治區(qū)衛(wèi)生健康委自籌經(jīng)費科研課題（Z-B20232038）