目的 建立銀杏葉提取物注射液藥物利用評(píng)價(jià)細(xì)則，基于加權(quán)TOPSIS法對臨床上使用銀杏葉提取物注射液的合理性情況進(jìn)行評(píng)價(jià)，為促進(jìn)其在臨床合理使用提供參考依據(jù)。方法 以銀杏葉提取物注射液說明書、指南、共識(shí)以及相關(guān)文獻(xiàn)為依據(jù)，制定銀杏葉提取物注射液藥物利用評(píng)價(jià)細(xì)則，采用加權(quán)TOPSIS法對亳州市人民醫(yī)院2023年1－12月228份使用銀杏葉提取物注射液病歷進(jìn)行評(píng)價(jià)。結(jié)果 228份病歷中，合理病歷（C_i≥0.8）有65例（28.51%），基本合理（0.6≤C_i＜0.8）有125例（54.82%），不合理病歷（C_i＜0.6）有38例（16.67%）。不合理用藥主要表現(xiàn)為給藥療程91例（39.91%）、滴注速度78例（34.21%）、相互作用52例（22.81%）、超醫(yī)保限制適應(yīng)證47例（20.61%）、超適應(yīng)證31例（13.60%）、用藥監(jiān)護(hù)28例（12.28%）和用藥前評(píng)估25例（10.96%）。結(jié)論 基于加權(quán)TOPSIS法的銀杏葉提取物注射液合理性評(píng)價(jià)辦法操作簡單，具有可行性，評(píng)價(jià)結(jié)果更加直觀合理。結(jié)果表明銀杏葉提取物注射液臨床使用較為不合理，醫(yī)院需加強(qiáng)干預(yù)，以期促進(jìn)臨床合理使用。

Objective To establish the rules for evaluating the drug utilization of Extract of Ginkgo Biloba Leaves Injection, and to evaluate the rationality of clinical use of Extract of Ginkgo Biloba Leaves Injection based on weighted TOPSIS method, so as to provide a reference basis for promoting its rational use in the clinic. Methods Based on the instruction manual of Extract of Ginkgo Biloba Leaves Injection, guidelines, consensus and related literature, formulated the rules for the evaluation of drug utilization, and evaluated 228 medical records using it from January to December 2023 in Bozhou People’s Hospital by the weighted TOPSIS method. Results Among the 228 medical records, there were 65 cases (28.51%) of reasonable medical records (C_i≥0.8), 125 cases (54.82%) of basically reasonable (0.6≤C_i＜0.8), and 38 cases (16.67%) of unreasonable medical records (C_i＜0.6). The main manifestations of irrational drug use included 91 cases (39.91%) of the course of administration, 78 cases (34.21%) of infusion speed, 52 cases (22.81%) of interaction, 47 cases (20.61%) of exceeding the medical insurance limitation, 31 cases (13.60%) of exceeding the indication, 28 cases (12.28%) of medication monitoring, and 25 cases (10.96%) of pre-medication assessment. Conclusion The rationality evaluation approach of Extract of Ginkgo Biloba Leaves Injection based on the weighted TOPSIS method is simple and feasible, and the evaluation results are more intuitive and reasonable. The results showed that the clinical use of the drug is more unreasonable, and hospitals need to strengthen the intervention, with a view to promoting rational clinical use.

R971；R972