青光眼是一種神經(jīng)退行性疾病，是全球范圍內(nèi)導(dǎo)致失明的主要原因。早期診斷和正確治療對(duì)于防治青光眼、預(yù)防視力障礙非常重要。白藜蘆醇是一種天然成分，具有多種活性，可通過降低眼壓，降低炎癥反應(yīng)，降低氧化應(yīng)激反應(yīng)，阻止細(xì)胞凋亡，促進(jìn)視神經(jīng)修復(fù)，改善線粒體生物合成對(duì)青光眼視網(wǎng)膜損傷發(fā)揮保護(hù)作用?？偨Y(jié)了白藜蘆醇防治青光眼的藥理作用研究進(jìn)展，分析其降低視網(wǎng)膜損傷的作用機(jī)制，為白藜蘆醇的臨床應(yīng)用提供支持。

Glaucoma is a neurodegenerative disease and the leading cause of blindness worldwide. Early diagnosis and proper treatment are crucial for the prevention and treatment of glaucoma and visual impairment. Resveratrol is a natural ingredient with multiple activities. Resveratrol can protect against glaucoma and retinal damage by reducing intraocular pressure, reducing inflammation, reducing oxidative stress, preventing cell apoptosis, promoting optic nerve repair, and improving mitochondrial biosynthesis. This article summarizes the research progress of resveratrol in prevention and treatment of glaucoma, analyzes its mechanism of reducing retinal damage, and provides support for the clinical application of resveratrol.

R988.1

河北省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目（213777108D）