中樞神經(jīng)系統(tǒng)疾病涵蓋了缺血性腦損傷、阿爾茨海默病、帕金森病和脊髓損傷等，當(dāng)下尚未發(fā)現(xiàn)非常有效的治療手段。丹參中最關(guān)鍵的有效成分當(dāng)屬丹參酮類(lèi)化合物，包含隱丹參酮、丹參酮I、丹參酮II_A、二氫丹參酮。丹參酮可以多維度、多途徑地改善中樞神經(jīng)系統(tǒng)疾病的神經(jīng)功能，防治腦卒中、脊髓損傷、記憶和認(rèn)知功能障礙、阿爾茨海默病、帕金森病、癲癇、多發(fā)性硬化癥、創(chuàng)傷后應(yīng)激障礙、抑郁癥等中樞神經(jīng)系統(tǒng)疾病。綜述了丹參酮防治中樞神經(jīng)系統(tǒng)疾病的研究進(jìn)展。

Central nervous system diseases include ischemic brain injury, Alzheimer's disease, Parkinson's disease, and spinal cord injury, among others, and currently no highly effective treatment has been found. The most critical active ingredients in Salviae Miltiorrhizae Radix et Rhizoma are tanshinone compounds, including cryptotanshinone, tanshinone I, tanshinone II_A, and dihydrotanshinone. Tanshinones can improve the neurological function of central nervous system diseases in multiple dimensions and pathways, preventing and treating central nervous system diseases such as stroke, spinal cord injury, memory and cognitive dysfunction, Alzheimer's disease, Parkinson's disease, epilepsy, multiple sclerosis, post-traumatic stress disorder, depression, etc. This article reviews the research progress on tanshinones in prevention and treatment of central nervous system diseases.

R285;R286.1