[關(guān)鍵詞]
[摘要]
心肌梗死已成為威脅人類健康的重要疾病之一。丹參酮ⅡA是從丹參中提取的有效成分,具有多種藥理活性,可通過舒張血管、延緩心肌纖維化進(jìn)程、抑制心肌細(xì)胞凋亡、減輕炎癥反應(yīng)、降低氧化應(yīng)激反應(yīng)、促進(jìn)新生血管形成發(fā)揮治療心肌梗死的作用。綜述了丹參酮ⅡA改善心肌梗死的藥理作用研究進(jìn)展,希望為丹參酮ⅡA的臨床應(yīng)用提供參考。
[Key word]
[Abstract]
Myocardial infarction has become one of the important diseases threatening human health. Tanshinone IIA is an active ingredient extracted fromSalviae Miltiorrhizae Radix etRhizoma, with various pharmacological activities. Tanshinone IIA can treat myocardial infarction by dilating blood vessels, delaying the progression of myocardial fibrosis, inhibiting myocardial cell apoptosis, reducing inflammatory response, lowering oxidative stress response, and promoting neovascularization. This article reviews the pharmacological research progress of tanshinone IIA in improving myocardial infarction, hoping to provide reference for the clinical application of tanshinone IIA.
[中圖分類號(hào)]
R285
[基金項(xiàng)目]
重慶市自然科學(xué)基金面上項(xiàng)目(CSTB2024NSCQ-MSX1301)