[關(guān)鍵詞]
[摘要]
腦缺血再灌注損傷是腦血管疾病主要的病理特征。黃芩苷可通過降低炎癥反應(yīng),減輕氧化應(yīng)激反應(yīng),抑制神經(jīng)組織細(xì)胞凋亡,減輕缺血性腦水腫,促進(jìn)神經(jīng)細(xì)胞增殖,調(diào)節(jié)腸道微生物群,增強(qiáng)孕酮活性降低腦缺血再灌注損傷,對神經(jīng)功能發(fā)揮保護(hù)作用??偨Y(jié)了黃芩苷對腦缺血再灌注損傷保護(hù)的研究進(jìn)展,為黃芩苷的臨床應(yīng)用提供循證支持。
[Key word]
[Abstract]
Cerebral ischemia-reperfusion injury is the main pathological feature of cerebrovascular diseases. Baicalin can reduce inflammation, alleviate oxidative stress, inhibit neural tissue cell apoptosis, alleviate ischemic brain edema, promote nerve cell proliferation, regulate gut microbiota, enhance progesterone activity, reduce cerebral ischemia-reperfusion injury, and protect neurological function. This article summarizes the research progress on the protection of baicalin against cerebral ischemia-reperfusion injury, providing evidence-based support for the clinical application of baicalin.
[中圖分類號]
R971
[基金項(xiàng)目]
河南省科技廳軟科學(xué)項(xiàng)目(242400410217)