[關(guān)鍵詞]
[摘要]
肝癌是嚴(yán)重威脅人類生命健康的消化系統(tǒng)惡性腫瘤，目前西醫(yī)臨床治療方面均存在諸多不良反應(yīng)和治療受限。在針對肝癌的研究中，中藥多糖已被證實能夠通過多種機(jī)制發(fā)揮抗癌功效，如誘導(dǎo)細(xì)胞凋亡、誘導(dǎo)細(xì)胞周期阻滯、阻斷血管生成、阻斷腫瘤的侵襲和轉(zhuǎn)移、促進(jìn)抗腫瘤免疫刺激活性、調(diào)節(jié)腸道菌群和靶向MircoRNA等?？偨Y(jié)了中藥多糖治療肝癌的作用機(jī)制，有望為肝癌的治療提供新的思路和策略。
[Key word]
[Abstract]
Hepatocellular carcinoma (HCC) is a malignant tumor of the digestive system that seriously threatens human life and health. At present, there are many adverse reactions and treatment limitations in the clinical treatment of HCC. In research on liver cancer, traditional Chinese medicine polysaccharides have been proven to exert anti-cancer effects through various mechanisms, such as inducing cell apoptosis, inducing cell cycle arrest, blocking angiogenesis, inhibiting tumor invasion and metastasis, promoting anti-tumor immune stimulatory activity, regulating intestinal flora, and targeting MircoRNA. This article summarizes the mechanism of action of traditional Chinese medicine polysaccharides in treatment of HCC, which is expected to provide new ideas and strategies for the treatment of HCC.
[中圖分類號]
R965;R979.1
[基金項目]
博士后研究人員落戶黑龍江科研啟動資助金項目（LBH-Q15141）；黑龍江省省屬高等學(xué)?；究蒲袠I(yè)務(wù)費科研項目（2022-KYYWF-0714）；黑龍江省中醫(yī)藥科研項目（ZHY2023-124）；黑龍江省大學(xué)生創(chuàng)新創(chuàng)業(yè)訓(xùn)練計劃項目（202310229019；202410229047）
