柴胡皂苷是從柴胡中提取的皂苷衍生物，具有多種藥理作用。柴胡皂苷可通過多種途徑對肝臟產(chǎn)生保護作用，如抗炎、調(diào)節(jié)肝臟代謝、抗肝纖維化、抗肝癌、抗氧化應激、調(diào)節(jié)細胞凋亡?？偨Y(jié)了柴胡皂苷對肝臟保護作用機制的研究進展，以期為肝臟疾病的新藥開發(fā)和臨床應用提供參考和借鑒。

Saikosaponins are saponin derivatives extracted from Bupleuri Radix and have various pharmacological effects. Saikosaponins have hepatoprotective effects through various pathways, such as anti-inflammatory actions, regulating hepatic metabolism, anti-liver fibrosis, anti-hepatic cancer, antioxidant stress, and regulating cell apoptosis. This article summarizes the research progress on the hepatoprotective mechanisms of saikosaponins, in order to provide reference and guidance for the development and clinical application of new drugs for liver diseases.

R286.5

國家自然科學基金資助項目（81603418、82074271）；黑龍江省優(yōu)秀青年人才項目（2020YQ05）；黑龍江中醫(yī)藥大學研究生創(chuàng)新科研項目立項（2024yjscx124）