[關鍵詞]
[摘要]
視網(wǎng)膜病變是糖尿病的主要微血管并發(fā)癥,給患者的日常生活造成嚴重威脅。紅景天苷可通過降低血糖水平、抑制視網(wǎng)膜細胞死亡、降低炎性損傷、減輕氧化應激損傷、抑制血管內(nèi)皮生長因子的表達、減輕谷氨酸興奮性毒性防治糖尿病視網(wǎng)膜病變??偨Y(jié)了紅景天苷用于糖尿病視網(wǎng)膜病變的藥理作用研究進展,為紅景天苷的臨床應用提供支持。
[Key word]
[Abstract]
Retinopathy is the main microvascular complication of diabetes, which poses a serious threat to the daily life of patient. Salidroside plays a role in preventing and treating diabetic retinopathy by lowering blood sugar levels, inhibiting retinal cell death, reducing inflammatory damage, reducing oxidative stress damage, inhibiting VEGF expression, and reducing glutamate excitotoxicity. This article summarizes the research progress on pharmacological effects of salidroside in diabetes retinopathy, and provides support for the clinical application of salidroside.
[中圖分類號]
R988.1;R977
[基金項目]