皮膚病已成為影響人類生活質量和身心健康的重要疾病，其臨床治療藥物存在作用機制單一、停藥易復發(fā)、個體療效差異較大、長期不良反應大等缺點。黃芩苷是黃芩中的黃酮類化合物，可通過減輕炎癥反應、減輕氧化損傷、抑制角質形成細胞過度增殖、保護皮膚屏障功能、阻止正常皮膚細胞死亡、防治皮膚癌發(fā)揮防治多種皮膚病變的作用?？偨Y了黃芩苷治療皮膚病的藥理作用研究進展，為黃芩苷臨床應用于皮膚病提供思路。

Skin diseases have become an important disease that affects human quality of life and physical and mental health. Their clinical treatment drugs have disadvantages such as a single mechanism, easy recurrence after discontinuation, significant individual efficacy differences, and large long-term adverse reactions. Baicalin is a flavonoid compound in Scutellariae Radix, which can prevent and treat various skin lesions by reducing inflammation response, alleviating oxidative damage, inhibiting excessive proliferation of keratinocytes, protecting skin barrier function, preventing normal skin cell death, and preventing skin cancer. This article summarizes the pharmacological research progress of baicalin in treatment of skin diseases, providing ideas for the clinical application of baicalin in prevention and treatment of skin diseases.

R285.5;R287.7

四川省科技計劃項目（2018JY0654）