[關(guān)鍵詞]
[摘要]
目的 探討婦炎康膠囊聯(lián)合陰道用乳桿菌活菌膠囊治療細(xì)菌性陰道病的臨床效果。方法 選取2017年3月—2018年3月在吉林醫(yī)藥學(xué)院附屬醫(yī)院診治的細(xì)菌性陰道病患者155例,隨機(jī)分成對(duì)照組(77例)和治療組(78例)。對(duì)照組患者每晚清潔外陰后陰道深部放入陰道用乳桿菌活菌膠囊,1粒/次;治療組患者在對(duì)照組基礎(chǔ)上口服婦炎康膠囊,6粒/次,3次/d。兩組患者均連續(xù)治療20 d。觀察兩組患者臨床療效,同時(shí)比較治療前后兩組患者臨床癥狀消失時(shí)間、陰道清潔度、改良胺試驗(yàn)和線索細(xì)胞轉(zhuǎn)陰率。結(jié)果 治療后,對(duì)照組和治療組臨床有效率分別為84.42%和96.15%,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療組患者白帶增多消失時(shí)間、外陰瘙癢消失時(shí)間及陰道異味消失時(shí)間均顯著早于對(duì)照組患者,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,治療組患者的陰道清潔度Ⅰ~Ⅱ度例數(shù)顯著多于對(duì)照組患者,改良胺試驗(yàn)及線索細(xì)胞轉(zhuǎn)陰率顯著高于對(duì)照組患者,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 婦炎康膠囊聯(lián)合陰道用乳桿菌活菌治療細(xì)菌性陰道病療效顯著,臨床癥狀消失時(shí)間短,安全性好,具有一定的臨床推廣應(yīng)用價(jià)值。
[Key word]
[Abstract]
Objective To investigate the clinical efficacy of Fuyankang Capsules combined with Live Lactobacillus Capsule for Vaginal Use in treatment of bacterial vaginosis. Methods Patients (155 cases) with bacterial vaginosis in Affiliated Hospital of Jilin Medical University from March 2017 to March 2018 were randomly divided into control (77 cases) and treatment (78 cases) groups. Patients in the control group were vagina near the deep administered with Live Lactobacillus Capsule for vaginal use after cleaning the vulva every night, 1 grain/time. Patients in the treatment group were po administered with Fuyankang Capsules on the basis of the control group, 6 grains/time, three times daily. Patients in two groups were treated for 20 d. After treatment, the clinical efficacy was evaluated, and the disappearance time of clinical symptoms, vaginal cleaning degree, ameliorated-Whiff test and negative rate of clue cells in two groups before and after treatment was compared. Results After treatment, the clinical efficacy in the control and treatment groups was 84.42% and 96.15% respectively, and there were differences between two groups (P<0.05). After treatment, the disappearance time of leukorrhagia, pruritus vulvae and vaginal odor in the treatment group was significantly earlier than that in the control group, with significant difference between two groups (P<0.05). After treatment, the cases of vaginal cleaningⅠ - Ⅱ degree in the treatment group were significantly more than patients in the control group, ameliorated-Whiff test and negative rate of clue cells in the treatment group was significantly higher than that in the control group, with significant difference between two groups (P<0.05). Conclusion Fuyankang Capsules combined with Live Lactobacillus Capsule for vaginal use has significant curative effect in treatment of bacterial vaginosis with high safty, and the disappearance time of clinical symptoms is earlier, which has a certain clinical application value.
[中圖分類號(hào)]
[基金項(xiàng)目]