藥物在腸道內(nèi)的吸收程度和吸收特征是影響口服藥物生物利用度的重要因素。腸道吸收研究可以預(yù)測影響藥物在腸道吸收的機制與因素，研究方法主要包括體內(nèi)法（in vivo）、在體法（in situ）、體外法（in vitro）等。就目前藥物小腸吸收的研究方法及其特點進(jìn)行綜述。

The degree and character of intestinal tract absorption is an important factor that affects bioavailability of oral drugs. The absorption study of intestinal tract, including in vivo, in situ, in vitro ,and so on, can predict mechanisms and factors that affect drug absorption in intestine. In this paper, the current methods of drug intestinal absorption and their characteristics are reviewed.

國家重大新藥創(chuàng)制專項(編號2009ZX09304-002)、國家自然科學(xué)基金(編號30772778)國家高等學(xué)校博士學(xué)科點專項科研基金 (編號200800630005)、國家中醫(yī)藥管理局中醫(yī)藥行業(yè)科研專項(編號200807051)資助。