灰樹花Grifola frondosa為擔(dān)子菌亞門、樹花菌屬真菌，是一種藥、食用菌。其化學(xué)成分有多糖、蛋白質(zhì)等，藥理作用涵蓋免疫調(diào)節(jié)、抗腫瘤、抗糖尿病、抗高脂血、抗病毒等方面。近年來，對灰樹花化學(xué)成分與藥理活性的研究受到了廣泛的關(guān)注，一些臨床試驗(yàn)也相繼開展。現(xiàn)對灰樹花的化學(xué)成分與藥理活性研究概況進(jìn)行綜述，以期為灰樹花的全面開發(fā)和深入研究提供參考。

Grifola frondosa, a species of Basidiomycotina, is an edible and medicinal fungus. Its chemical constituents include polysaccharides and proteins as well. The pharmacological effect of G. frondosa covers immunomodulatory, antidiabetic, anti-hyperlipidemia, antivirus, and antitumor effects, etc. The chemical constituents of G. frondosa and the researches on pharmacological effect of G. frondosa have been concerned widely. And some clinical trials have been carried out in recent years. Recent studies on chemical constituents and pharmacological effect of G. frondosa were reviewed in this paper. Moreover, references for the full development and in-depth study of G. frondosa have been offered.