毒性病理同行評議（peer review）的目的是核實(shí)病理診斷和病理解釋的正確性，提高病理報(bào)告的質(zhì)量，執(zhí)行的時(shí)機(jī)通常在試驗(yàn)總報(bào)告完成前。負(fù)責(zé)同行評議的病理學(xué)家將復(fù)查足夠的切片和病理數(shù)據(jù)，幫助試驗(yàn)病理學(xué)家進(jìn)一步確認(rèn)、精煉病理診斷和數(shù)據(jù)解釋。同行評議需篩選復(fù)查的材料由試驗(yàn)病理學(xué)家提供，必要時(shí)，可臨時(shí)成立病理專家小組來解決爭議或分歧。試驗(yàn)病理學(xué)家根據(jù)同行評議討論產(chǎn)生的結(jié)果對病理數(shù)據(jù)和病理報(bào)告進(jìn)行相應(yīng)修改，并簽署最終病理報(bào)告，是唯一對試驗(yàn)最終病理數(shù)據(jù)和病理報(bào)告內(nèi)容負(fù)責(zé)的人。同行評議病理學(xué)家需出具簽名的同行評議報(bào)告，報(bào)告中描述同行評議的程序，確認(rèn)試驗(yàn)病理學(xué)家的病理報(bào)告是正確、恰如其分地反應(yīng)病理數(shù)據(jù)。試驗(yàn)的病理學(xué)家也需要在同行評議報(bào)告上簽名，以表明同意同行評議病理學(xué)家的觀點(diǎn)?？偨Y(jié)了毒性病理同行評議當(dāng)前執(zhí)行的類型和模式推薦，可根據(jù)特定試驗(yàn)需要而進(jìn)行改變。

The aim of peer review on toxicological pathology is to verify and improve the accuracy and quality of pathology diagnoses and data interpretations. The peer review on toxicological pathology is commonly performed before a study report completed. The peer review pathologist will review enough biopsys and pathological data to assist the study pathologist in refining pathology diagnoses and data interpretations. Data supplied by the study pathologist are to be reviewed and selected by the peer review pathologist. The consultations with the additional experts or a pathological panel may be used to resolve discrepancies if necessary. The study pathologist is solely responsible for the content of the final pathological data and reports, modifies the results according to the peer review discussions, and signs the final pathologist’s report. The peer review pathologist should give a signed peer review report with describing the peer review process and confirming that the study pathologist’s report could accurately and appropriately reflect the pathology data. The study pathologist also needs to check back and sign his or her name on the peer review report, which is proved to agree with the peer review pathologist. The types and modes currently implemented by the peer review on toxicological pathology should be recommended and may be modified to meet the demand of a specific study.