目的 對(duì)ADVIA 2120血細(xì)胞分析儀的動(dòng)物血細(xì)胞分析性能進(jìn)行評(píng)價(jià)。方法 對(duì)該儀器的準(zhǔn)確度、精密度、線性和攜帶污染率進(jìn)行評(píng)價(jià)，并與Hemavet 950FS動(dòng)物血細(xì)胞分析儀測(cè)定結(jié)果及人工白細(xì)胞分類鏡檢結(jié)果進(jìn)行比較。結(jié)果 該儀器的準(zhǔn)確度、批內(nèi)和批間精密度、攜帶污染率和線性均在允許范圍內(nèi)；與Hemavet 950FS動(dòng)物血細(xì)胞分析儀測(cè)定結(jié)果相關(guān)性白細(xì)胞（WBC）、紅細(xì)胞（RBC）、血紅蛋白（HGB）、血小板（PLT）較好，紅細(xì)胞壓積（HCT）較差；白細(xì)胞分類測(cè)定結(jié)果與人工顯微鏡分類比較，中性粒細(xì)胞、淋巴細(xì)胞、嗜酸粒細(xì)胞相關(guān)性較好，單核細(xì)胞、嗜堿粒細(xì)胞相關(guān)性較差。結(jié)論 ADVIA 2120全自動(dòng)血細(xì)胞分析儀在測(cè)定動(dòng)物全血樣本時(shí)準(zhǔn)確度、精密度、線性較好，攜帶污染率低，有較強(qiáng)的篩選能力，是一臺(tái)性能良好的全自動(dòng)血細(xì)胞分析儀，可以滿足藥物安全性評(píng)價(jià)課題動(dòng)物血液樣本分析的需要。

Objective To evaluate the performance of ADVIA 2120 Hematology Analyzer on blood cell analysis of common laboratory animals. Methods The blood samples were analysed by ADVIA 2120 Hematology Analyzer in terms of accuracy, precision, linearity, and the contamination rate. The results were compared with those of Hemavet 950FS Blood Cell Counter as well as manual blood smears under microscopy. Results The values of the accuracy, precision, linearity, and the contamination rate were all below the qualified standardization. ADVIA 2120 had a good correlation with Hemavet 950FS in WBC, RBC, HGB, and PLT. It also correlated very well with the manual blood smears under microscopy such as neutrophil, lymphocyte, and eosinophil, although some differences were observed in the results of monocyte and basophil. Conclusion The performance of ADVIA 2120 is good and reliable. It could satisfy the hematological analysis of drug evaluation studies.