目的 對(duì)以三七提取物、黃芪提取物、靈芝提取物等為原輔料制成的保健食品七花牌七靈寶軟膠囊，依據(jù)《保健食品檢驗(yàn)與評(píng)價(jià)技術(shù)規(guī)范》（2003年版）進(jìn)行緩解體力疲勞功能研究。方法 根據(jù)人口服推薦用量，設(shè)樣品低、中、高劑量組分別為200、400、800 mg/kg（分別相當(dāng)于人體推薦用量的5、10、20倍），同時(shí)設(shè)一個(gè)陰性對(duì)照組，每組10只動(dòng)物。分別ig 給予10、20、40 mg/mL的七靈寶軟膠囊溶液，給藥體積為20 mL/kg，對(duì)照組給予等體積的玉米胚芽油，每天1次，連續(xù)30 d。結(jié)果 該樣品對(duì)小鼠的體質(zhì)量增長(zhǎng)無(wú)影響；具有延長(zhǎng)小鼠的負(fù)重游泳時(shí)間的作用；能減少或抑制疲勞小鼠血清尿素氮的產(chǎn)生；具有促進(jìn)小鼠的肝糖原儲(chǔ)備的作用；能減少小鼠運(yùn)動(dòng)后的血乳酸曲線下面積。結(jié)論 七花牌七靈寶軟膠囊具有緩解小鼠體力疲勞的作用。

Objective To evaluate the relieving physical fatigue function of health food Qilingbao Soft Capsule (QSC) with Qihua Barnd which was made from the extracts of Notoginseng Radix, Astragali Radix, Ganoderma Lucidum seu Japonicum, and so on, according to “Health food Inspection and Evaluation Technical Specifications” (2003). Methods According to the recommended oral dosage, the mice were divided into control, low-, mid-, and high-dose (200, 400, 800 mg/kg, equivalent to 5, 10 and 20 times of recommended dosage for human body) groups, 10 mice in each group. The mice in treatment groups were administered with QSC (10, 20, and 40 mg/mL, with the volume of administration 20 mL/kg) while the mice in the control group were given equal volume of corn oil, once daily for continuous 30 d. Results The samples had no effect on the increase of body weight in mice, had the function of prolonging the weight-bearing swimming time in mice, could reduce or inhibit the generation of serum urea in mice with fatigue, had the effect of promoting the liver glycogen reserves of mice, and decreased the area under blood lactate curve of mouse postexercise. Conclusion The QSC has the function of relieving the physical fatigue in mice