目的 考察玻璃瓶、聚氯乙烯軟袋（PVC）、聚丙烯可立袋（PP）、非聚氯乙烯復(fù)合膜軟袋（NPVC）4種包裝材料在葡萄糖和氯化鈉兩種溶媒大輸液中對丹參酮Ⅱ_A磺酸鈉注射液的吸附情況。方法 將丹參酮Ⅱ_A磺酸鈉注射液分別配制于4種材質(zhì)的0.9%氯化鈉注射液及5%葡萄糖注射液中，于0、0.25、0.5、1、2、4、6 h取樣，用紫外可見分光光度法測定丹參酮Ⅱ_A磺酸鈉的吸光度值，考察其量的變化。結(jié)果 6 h內(nèi)丹參酮Ⅱ_A磺酸鈉在4種材質(zhì)兩種輸液中量的變化低于±4%，組間比較差異無顯著性（P＞0.05）。結(jié)論 丹參酮Ⅱ_A磺酸鈉注射液在4種不同材質(zhì)的輸液中穩(wěn)定性良好。

Objective To investigate the absorptivities of Sulfotanshinone Sodium Injection (SSI) in glass bottles, polyvinylidene chlorid (PVC) plastic infusion bags, polypropylene plastic (PP) infusion bottles and non-polyvinylidene chlorid (NPVC) infusion bags respectively for 6 h. Methods The drugs were separately added to different infusion sets. The samples of drug solutions were collected after 0, 0.25, 0.5, 1, 2, 4, and 6 h and analyzed by UV methods. Results The changes of the sulfotanshinone sodium contents in each compatible solution within 6 h were less than 4% (P > 0.05). Conclusion SSI has the good stability in the infusion sets made of four different meterials.

深圳市科技計劃項目（200903048）