目的 考察五倍子不同產(chǎn)地（河北曲陽、浙江嘉興、湖南桑植、陜西西鄉(xiāng)、云南鳳縣）的體外抗菌作用。方法 五倍子醇提浸膏用倍半稀釋法稀釋成不同濃度藥液，采用管碟法測定各產(chǎn)地五倍子的最小抑菌濃度（MIC）。結(jié)果 河北、浙江、湖南、陜西、云南所產(chǎn)五倍子醇提浸膏對金黃色葡萄球菌的MIC依次為6.25、1.562 5、1.562 5、3.125、0.781 25 mg/L；對大腸桿菌的MIC依次為3.125、12.5、6.25、6.25、3.125 mg/L；對白色念珠菌的MIC依次為6.25、1.562 5、3.125、1.562 5、3.125 mg/L；對綠膿桿菌的MIC依次為12.5、6.25、6.25、6.25、3.125 mg/L。結(jié)論 河北、浙江、陜西、云南、湖南所產(chǎn)五倍子均有抑菌作用，其中云南產(chǎn)五倍子醇提物對金黃色葡萄球菌、大腸桿菌、綠膿桿菌抑菌作用最強，陜西、浙江產(chǎn)五倍子醇提物對白色念球菌的抑菌作用強。

Objective To evaluate the in vitro antibacterial activity of ethanol extract from Galla Chinensis (EEGC) from different origins (Hebei, Zhejiang, Hunan, Shaanxi, and Yunnan provinces). Methods EEGC was diluted into different concentration by half times dilution method. Minimum inhibitory concentration (MIC) of Galla Chinensis from different origins was determined by cylinder-plate method. Results The MIC values of EEGC from above five provinces against Staphylococcus aureus were 6.25, 1.562 5, 1.562 5, 3.125, and 0.781 25 mg/L. The MIC values against Escherichia coli were 3.125, 12.5, 6.25, 6.25, and 3.125 mg/L. The MIC values against C. albicans were 6.25, 1.562 5, 3.125, 1.562 5, and 3.125 mg/L. The MIC values against Pseudomonas aeruginosa were 12.5, 6.25, 6.25, 6.25, and 3.125 mg/L. Conclusion Galla Chinensis from the five provinces all have bacteriostatic action, EEGC from Yunnan province has the strongest bacteriostatic action against S. aureus, E. coli, and P. aeruginosa. In addition, EEGC from Shaanxi and Zhejiang province exhibites the notable bacteriostatic action against C. albicans.