目的 探討左氧氟沙星致心血管不良反應(yīng)的一般規(guī)律與特點(diǎn)。方法 對(duì)福建省長(zhǎng)樂(lè)市醫(yī)院2010年1月—2013年3月上報(bào)的12例左氧氟沙星所致的心血管不良反應(yīng)報(bào)告表進(jìn)行統(tǒng)計(jì)、分析。結(jié)果 左氧氟沙星致心血管不良反應(yīng)在老年患者發(fā)生率較高，多在用藥2 h內(nèi)發(fā)生。臨床表現(xiàn)復(fù)雜多樣，主要表現(xiàn)為心悸和心臟不適，嚴(yán)重者可出現(xiàn)心臟傳導(dǎo)阻滯。結(jié)論 臨床上應(yīng)重視左氧氟沙星的心血管不良反應(yīng)，堅(jiān)持合理用藥。

Objective To explore the cardiovascular adverse reactions caused by the general rules and characteristics of Levofloxacin. Methods Twelve cases of cardiovascular adverse reactions reports in Fujian Changle Hospital from January 2010 to March 2013 were statistically analyzed. Results Cardiovascular adverse reactions caused by Levofloxacin were mostly happened in the elderly patients 2 h after the medication. There were complex and diverse clinical manifestations, such as heart palpitations and cardiac discomfort, and even serious heart block. Conclusion The clinical application of Levofloxacin should be seriously monitored, in order to reduce the occurrence of cardiovascular adverse reactions.