[關(guān)鍵詞]
[摘要]
目的 探討杜仲多糖對(duì)兔心肌缺血再灌注損傷的保護(hù)作用。方法 將兔隨機(jī)分為4組(每組8只),即假手術(shù)組、缺血再灌注組、丹參片預(yù)處理組、杜仲多糖預(yù)處理組。監(jiān)測(cè)各組兔血清心肌酶譜、超氧化物歧化酶(SOD)、丙二醛(MDA)等水平的變化。結(jié)果 杜仲多糖預(yù)處理組心肌酶、SOD、MDA含量與缺血再灌注組、丹參預(yù)處理組比較差異顯著(P<0.05)。結(jié)論 杜仲多糖對(duì)兔心肌缺血再灌注損傷能夠產(chǎn)生較好的保護(hù)作用。
[Key word]
[Abstract]
Objective To demonstrate the effect of Eucommia ulmoides polysaccharides (EUP) on rabbit myocardial ischemia- reperfusion injury model. Methods Rabbits were divided into four groups including Sham group, ischemia-reperfusion group, groups pretreated with Salvia miltiorrhiza and EUP. And the indexes of CK, CK-MB, LDH, AST, SOD, and MDA were detected. Results Results showed that those indexes in group pretreated with EUP differed significantly from other groups (P < 0.05). Conclusion It shows that EUP may decrease the injury of myocardial ischemia-reperfusion so as to get the better protection of rabbits.
[中圖分類號(hào)]
[基金項(xiàng)目]