[關(guān)鍵詞]
[摘要]
綜合評述常用中藥體外抑菌評價方法及存在問題,發(fā)現(xiàn)評價標(biāo)準(zhǔn)未能統(tǒng)一,結(jié)果受主觀因素影響大、體外與體內(nèi)抑菌效果存在一定差異性,未能結(jié)合中藥特點(diǎn)選擇合適的方法。不同抑菌方法對評價中藥對細(xì)菌的抑制能力(抑菌環(huán)、MIC)、殺滅能力(MBC),細(xì)菌對藥物的耐藥率等影響較大。中藥體外抑菌作用雖然研究方法較多,應(yīng)根據(jù)研究對象、實(shí)驗?zāi)康?、具體條件等選擇合適的方法,以便更加準(zhǔn)確地評價中藥的抗菌作用。
[Key word]
[Abstract]
After the common evaluation methods of in vitro bacteriostasis by Chinese materia medica (CMM) and the existing problems were comprehensively reviewed, we found that the evaluation criterion was not unified. The results were affected by subjective factors, there were some differences in the antibacterial effect between in vitro and in vivo, and the appropriate method was chosen without combining with the characteristics of CMM. Different bacteriostatic methods had a greater influence on the evaluation of CMM inhibition of bacteria (bacteriostasis circle, MIC), ability to kill (MBC), and the resistance of bacteria to drugs, etc. There are many research methods on the bacteriostasis experiment in vitro of CMM. Therefore, suitable methods should be chosen according to the conditions, aims, and requirements, so as to evaluate the antibacterial effect of CMM more accurately.
[中圖分類號]
[基金項目]