[關(guān)鍵詞]
[摘要]
臨床生化指標主要用來檢測碳水化合物、脂類、蛋白質(zhì)、尿液、肝膽、心血管、肌肉、胃腸道系統(tǒng)的代謝。臨床檢驗的個體或匯總數(shù)據(jù)要在病理報告中分析并在實驗報告中述及。闡明了臨床生化指標在藥物臨床前研究中的毒理學(xué)和生物學(xué)意義,從而考察和反映了臨床生化指標對動物機體總的代謝、營養(yǎng)和健康狀態(tài)的影響,同時為建立和定期更新實驗室各實驗動物臨床檢驗的背景值提供了參考與比較。
[Key word]
[Abstract]
Clinical biochemistry indicators can be used for the test of the metabolism of carbohydrates, lipids, proteins, urine, hepatobiliary, cardiovascular, musculoskeletal, and gastrointestinal systems. Individual and summary data of clinical examination should be analyzed in the pathology report and described in the study report. This paper expounds the toxicological and biological significance of clinical biochemical indicators in drug preclinical studies, in order to study and reflect their impacts to the total metabolism, nutrition, and health status in the animal body, and to establish and termly update the background baseline of each experimental animal in CRO's clinical pathology lab for reference and comparison.
[中圖分類號]
[基金項目]