水柏枝來(lái)源于檉柳科水柏枝屬植物水柏枝Myricaria germanica及同屬多種植物的嫩枝, 具有疏風(fēng)解表、祛風(fēng)通絡(luò)、透疹止咳等功效。主要對(duì)來(lái)源于該屬的三春水柏枝M. paniculata、寬苞水柏枝M. bracteata和秀麗水柏枝M. elegans的黃酮類、三萜類、沒(méi)食子酸類、酚酸類、木脂素類、長(zhǎng)鏈脂肪醇類等6類化學(xué)成分以及它們的藥理活性研究進(jìn)展進(jìn)行綜述, 包括抗菌、抗炎、細(xì)胞免疫、抗疲勞、抗氧化、肝損傷保護(hù), 為進(jìn)一步開(kāi)發(fā)利用該屬植物、為新藥研發(fā)儲(chǔ)備先導(dǎo)化合物奠定基礎(chǔ)。

Myricaria germanica (Tamaricaceae) stems from the twigs in the plants of Myricaria Desv. It has the effects of dispelling wind to resolve exterior syndrome, dispelling pathogenic wind and removing obstruction in the meridians, promoting eruption and relieving a cough. The progress on the research of chemical constituents from M. paniculata, M. bracteata, and M. elegans, which mainly contain flavonoids, triterpenoids, gallic acids, phenolic acids, lignans, and long-chain alkanediols with the pharmacological activities such as antibiosis, anti-imflammation, anti-arthritis, cellular immunity, antifatigue, antioxidant, and hepatoprotective effects, was summarized. It establishs good chemical constituents foundation for development and utilization the resource of Myricaria and new drugs research and development.

國(guó)家自然科學(xué)基金資助項(xiàng)目(21072233)