目的 探討丹芍消炎合劑聯(lián)合靜脈抗生素治療濕熱型亞急性盆腔炎的臨床效果。方法 83 例確診為亞急性盆腔炎患者隨機(jī)分為2 組;對照組41 例,每12 h 靜脈滴注頭孢西丁2 g(頭孢類過敏者改用克林霉素1 g),使用至臨床癥狀、體征改善后的24 h,同時po 強(qiáng)力霉素100 mg,2 次/d,共2 周;治療組42 例,在對照組基礎(chǔ)上po 芍消炎合劑35 mL/次,3次/d,連續(xù)2 周,比較兩組患者的臨床療效與不良反應(yīng)。結(jié)果 治療組的總有效率為97.6%、愈顯率76.1%,靜脈抗生素使用(3.52±0.94)d;對照組總有效率90.24%、愈顯率29.2%,靜脈抗生素使用(4.95±1.18)d,兩組比較差異有統(tǒng)計學(xué)意義(P<0.01);且兩組均未發(fā)生不良反應(yīng)。結(jié)論 丹芍消炎合劑聯(lián)合靜脈抗生素治療亞急性盆腔炎療效確切,能明顯改善患者的臨床癥狀、縮短靜脈抗生素的使用時間,值得臨床推廣應(yīng)用。

Objective To investigate clinical effect of Danshao Anti-inflammatory Liquid combined with levofloxacin therapy in the treatment of subacute pelvic inflammatory disease. Methods Eighty-three patients with chronic pelvic inflammatory disease were randomly divided into control (n = 41) and treatment (n = 42) groups. The patients in the control group were iv administered with levofloxacin 2 g per 12 h and po administered with levofloxacin 100 mg, 2 time/d, for 14 d. While the patients in the treatment group were po administered with Danshao Anti-inflammatory Liquid, 35 mL/time, 3 time/d. Clinical effects of the two groups were compared. Results After treatment, the treatment group had total effective rate as 97.6%, which was obviously higher than that of the control group (90.24%). The difference between the two groups was statistical significant (P < 0.01). In addition, the using of the combination solution of Danshao Anti-inflammatory Liquid and vein antibiotics could decrease the using period of vein antibiotics. Conclusion Danshao Anti-inflammatory Liquid combined with levofloxacin therapy provides precise effect in treating subacute pelvic inflammatory disease, can remarkably improve clinical symptoms in patients, and it is worthy of promotion and application.

上海市科學(xué)技術(shù)委員會科研計劃項目課題(12401901904)