目的 探討不同心衰藥物對(duì)老年心衰患者的效果,并評(píng)價(jià)其經(jīng)濟(jì)學(xué)情況,以期選擇合適方法,降低醫(yī)療費(fèi)用支出。方法 選取2012年1月—2015年1月56例老年心衰患者為研究對(duì)象,隨機(jī)分成2組,每組28例。對(duì)照組予去乙酰毛花苷注射液治療,觀察組予毒毛花苷K注射液治療,觀察治療后在藥效和經(jīng)濟(jì)學(xué)指標(biāo)變化情況。結(jié)果 療效上,對(duì)照組與觀察組心血管不良事件發(fā)生率均為21.42%,兩組比較差異無統(tǒng)計(jì)學(xué)意義;對(duì)照組血小板減少、味覺障礙、肝腎功能損害、消化道反應(yīng)、皮疹發(fā)生率分別為17.86%、10.71%、14.29%、17.86%、7.14%;觀察組血小板減少、味覺障礙、肝腎功能損害、消化道反應(yīng)、皮疹發(fā)生率分別為14.29%、10.71%、17.86%、14.29%、10.71%,兩組差異無統(tǒng)計(jì)學(xué)意義;兩組治療后血小板、中性粒細(xì)胞、凝血酶原時(shí)間(PT)、活化部分凝血活酶時(shí)間(APTT)較治療前無變化,治療前后比較差異無統(tǒng)計(jì)學(xué)意義;對(duì)照組每盒單價(jià)為52.31元,觀察組每盒為12.61元,加上各自的其他治療費(fèi)用,對(duì)照組平均為(6 415.45±535.56)元/人,觀察組為(4 884.25±243.45)元/人,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 毒毛花苷K治療老年心衰效果與去乙酰毛花苷注射液相當(dāng),醫(yī)療費(fèi)用支出較低,更加經(jīng)濟(jì)實(shí)惠。

Objective To investigate the regimen efficacy of different prescriptions in elderly patients with heart failure, and evaluate the economic situation, in order to choose the right method and decrease the medicine fee. Methods The elderly patients (56 cases) with heart failure from January 2010 to January 2013 were chosen and divided into two groups, the control group had 28 cases, given Deslanoside Injection, the observation group had 28 cases, given Strophanthin K Injection, the effectiveness and economic indicators after treatment were observed. Results The incidence of cardiovascular adverse events in control group was 21.42%, the observation group was 21.42%, without significant difference (P > 0.05). The incidence of thrombocytopenia, taste disorders, liver and kidney function damage, gastrointestinal tract reaction in control group were 17.86%, 10.71%, 14.29%, 17.86%, and 7.14%, while those in the observation group were 14.29%, 10.71%, 17.86%, 14.29%, and 10.71%, without significant difference (P > 0.05). The platelets, neutrophils, PT, and APTT of two groups after treatment had no significant differences (P > 0.05), and the each unit price of control group was 52.31 yuan, the observation group was 12.61%, with their other treatment, the control group average was (6 415.45 ± 535.56) yuan/person, while that in the observation group was (4 884.25 ± 243.45) yuan/person,with statistical significance (P < 0.05). Conclusion Strophanthin K Injection in treatment of heart failure in elder patients had obviously efficacy, the medical expense was low and more economical and practical.