目的 探討鹵米松乳膏聯(lián)合青鵬軟膏治療局限性濕疹臨床效果。方法 選取2012年1月—2013年1月150例局限性濕疹患者為研究對(duì)象,隨機(jī)分成2組,對(duì)照組75例,予鹵米松乳膏治療,觀察組75例,在對(duì)照組基礎(chǔ)上加用青鵬軟膏治療,觀察治療后相關(guān)指標(biāo)變化情況。結(jié)果 總療效上,對(duì)照組痊愈率24%、總有效率81.34%,觀察組痊愈率34.67%、總有效率90.67%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);癥狀積分上,兩組治療后瘙癢積分、皮損積分、丘疹積分、紅斑積分較治療前均明顯下降,治療前后比較差異均有統(tǒng)計(jì)學(xué)意義(P<0.05),觀察組治療后在以上癥狀積分上較對(duì)照組治療后改善更加明顯,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);不良反應(yīng)上,對(duì)照組不良反應(yīng)總發(fā)生率為20%,觀察組不良反應(yīng)發(fā)生率為5.33%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);遠(yuǎn)期效果上,對(duì)照組復(fù)發(fā)率28%,皮損縮小面積為51%,癥狀積分為(3.12±0.53)分;觀察組復(fù)發(fā)率6.67%,皮損縮小面積為71%,癥狀積分為(1.11±0.34)分,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 鹵米松乳膏聯(lián)合青鵬軟膏治療局限性濕疹近遠(yuǎn)期療效滿意。

Objective To investigate the clinical efficacy of Halogen Betamethasone Cream (HBC) combined with Qingpeng Ointment (QO) in treatment of localized eczema, in order to choose the best drug and improve the clinical treatment level. Methods Patients (150 cases) with localized eczema from January 2012 to January 2013 were chosen, and divided into two groups, each group had 75 cases. The control group were given HBC, the observation were taken with QO on the base of control group, the relevant index changes were observed. Results The total healing rate of control group was 24%, the total efficacy was 81.34%, while those in the observation group were 34.67% and 90.67%., which had significant differences (P < 0.05). The itching, skin lesions, integral, pimples, erythema, integral symptom score of two groups after treatment were lower than before, with significant difference (P < 0.05). The score of observation group decreased more obviously than that of control group (P < 0.05). The adverse reactions rate of control group was 20%, while that in the observation group was 5.33%, with significant difference (P < 0.05). In long-term efficacy, the recurrence rate of control group was 28%, the skin contraction area was 51%, the symptom score was (3.12 ± 0.53), while those in the observation group were 6.67%, 71%, and (1.11 ± 0.34), with significant differences (P < 0.05). Conclusion The recent and forward efficacy of HBC combined with QO in treatment of localized eczema is satisfactory.